Reactome | KTN1 [endoplasmic reticulum membrane]

KTN1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-201604

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Kinectin

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q86UP2 KTN1

Gene Names

KTN1, CG1, KIAA0004

Chain

chain:1-1357

Reference Genes

BioGPS Gene:3895 KTN1

COSMIC (genes):KTN1 KTN1

CTD Gene:3895 KTN1

dbSNP Gene:3895 KTN1

ENSEMBL:ENSG00000126777 KTN1

HGNC:6467 KTN1

KEGG:hsa:3895 KTN1

Monarch:3895 KTN1

NCBI Gene:3895 KTN1

OMIM:600381 KTN1

UCSC:Q86UP2 KTN1

Reference Transcript

Participates

as a member of

RHOG endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Homo sapiens)

as a component of

KTN1 [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

KTN1 [endoplasmic reticulum lumen]

p-KTN1 [endoplasmic reticulum lumen]

KTN1 [plasma membrane]

Inferred To

ktn1 [endoplasmic reticulum membrane] (Danio rerio)

ktn1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

KTN1 [endoplasmic reticulum membrane] (Bos taurus)

KTN1 [endoplasmic reticulum membrane] (Canis familiaris)

KTN1 [endoplasmic reticulum membrane] (Gallus gallus)

KTN1 [endoplasmic reticulum membrane] (Sus scrofa)

Ktn1 [endoplasmic reticulum membrane] (Mus musculus)

Ktn1 [endoplasmic reticulum membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001072990.1, XP_054232004.1, XP_016876772.1, XP_054232006.1, XP_054232005.1, NP_001257943.1, XP_054232012.1, NP_001389622.1, NP_001389620.1, XP_054232009.1, XP_054232007.1, NP_001389615.1, NP_001389611.1, XP_011535055.1, NP_001389623.1, NP_001389614.1, XP_011535053.1, XP_054232008.1, XP_006720201.1, XP_006720202.1, XP_016876767.1, NP_004977.2, XP_016876771.1, NP_001072989.1

OpenTargets

ENSG00000126777

ENSEMBL

ENST00000413890, ENST00000438792, ENSP00000378725, ENSP00000378719, ENST00000395311, ENST00000459737, ENST00000395314, ENSG00000126777, ENSP00000432149, ENSP00000394992, ENST00000395308, ENSP00000391964, ENSP00000378720, ENSP00000378722, ENST00000395309

HPA

ENSG00000126777-KTN1

GeneCards

KTN1

PRO

Q86UP2

Pharos - Targets

Q86UP2

GlyGen

Q86UP2

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BXN2 CLEC7A	2	p-Y15-CLEC7A [plasma membrane] (R-HSA-5607641) CLEC7A [plasma membrane] (R-HSA-2130683)	0.556	3
UniProt:P51665 PSMD7	5	PSMD7 [cytosol] (R-HSA-68806) PSMD7 [nucleoplasm] (R-HSA-174309) PSMD7 [secretory granule lumen] (R-HSA-6801008) PSMD7 [extracellular region] (R-HSA-6806488) PSMD7 [ficolin-1-rich granule lumen] (R-HSA-6800406)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.483	11

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