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BMPRII dimer [plasma membrane]
Stable Identifier
R-HSA-201465
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
BMP type II receptor dimer
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by BMP (Homo sapiens)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Homo sapiens)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
An anchoring protein, Endofin, recruits R-Smad1/5/8 (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP2 binds to the receptor complex (Homo sapiens)
BMP:BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
Formation of a heteromeric BMP receptor complex (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
I-Smad competes with R-Smad1/5/8 for type I receptor (Homo sapiens)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
Phospho-R-Smad1/5/8 dissociates from the receptor complex (Homo sapiens)
BMP:p-BMPR:Endofin [early endosome membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
Type II receptor phosphorylates type I receptor (Homo sapiens)
BMP:BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
Participants
components
2 x
Type II receptor [plasma membrane] (Homo sapiens)
Participant Of
input
Formation of a heteromeric BMP receptor complex
hasComponent
BMP:BMPRII:p-4S-BMPRI [plasma membrane]
BMP:p-BMPR:Endofin [early endosome membrane]
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane]
BMPRII:BMPRI [plasma membrane]
Inferred To
BMPRII dimer [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Caenorhabditis elegans)
BMPRII dimer [plasma membrane] (Canis familiaris)
BMPRII dimer [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Drosophila melanogaster)
BMPRII dimer [plasma membrane] (Gallus gallus)
BMPRII dimer [plasma membrane] (Mus musculus)
BMPRII dimer [plasma membrane] (Rattus norvegicus)
BMPRII dimer [plasma membrane] (Sus scrofa)
BMPRII dimer [plasma membrane] (Xenopus tropicalis)
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