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BMPRII dimer [plasma membrane]
Stable Identifier
R-HSA-201465
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
BMP type II receptor dimer
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by TGF-beta family members (Homo sapiens)
Signaling by BMP (Homo sapiens)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Homo sapiens)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
An anchoring protein, Endofin, recruits R-Smad1/5/8 (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP2 binds to the receptor complex (Homo sapiens)
BMP:BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
Formation of a heteromeric BMP receptor complex (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
I-Smad competes with R-Smad1/5/8 for type I receptor (Homo sapiens)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
Phospho-R-Smad1/5/8 dissociates from the receptor complex (Homo sapiens)
BMP:p-BMPR:Endofin [early endosome membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
Type II receptor phosphorylates type I receptor (Homo sapiens)
BMP:BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII:BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Homo sapiens)
BMPRII dimer [plasma membrane] (Homo sapiens)
Participants
components
2 x
Type II receptor [plasma membrane] (Homo sapiens)
Participant Of
input
Formation of a heteromeric BMP receptor complex
hasComponent
BMP:BMPRII:p-4S-BMPRI [plasma membrane]
BMP:p-BMPR:Endofin [early endosome membrane]
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane]
BMPRII:BMPRI [plasma membrane]
Inferred To
BMPRII dimer [plasma membrane] (Bos taurus)
BMPRII dimer [plasma membrane] (Caenorhabditis elegans)
BMPRII dimer [plasma membrane] (Canis familiaris)
BMPRII dimer [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Drosophila melanogaster)
BMPRII dimer [plasma membrane] (Gallus gallus)
BMPRII dimer [plasma membrane] (Mus musculus)
BMPRII dimer [plasma membrane] (Rattus norvegicus)
BMPRII dimer [plasma membrane] (Sus scrofa)
BMPRII dimer [plasma membrane] (Xenopus tropicalis)
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