The mature dimeric BMP2 binds with high affinity to its signalling receptor, the type II receptor serine/threonine kinase. The type II receptor is known to form dimeric complexes even in the absence of BMP2 (Rosenzweig et al.1995).
Miyazono, K, Cox, GN, Okadome, T, Yamashita, H, Rosenzweig, BL, ten Dijke, P, Heldin, CH, Imamura, T
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