Reactome | p-4S-BMPR1A [plasma membrane]

p-4S-BMPR1A [plasma membrane]

Stable Identifier

R-HSA-201448

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

p-S215,S216,S218,S220-BMPR1A, Phospho-Bone morphogenetic protein receptor type IA, BMRA_HUMAN, BMPR1A

Icon

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P36894 BMPR1A

Gene Names

BMPR1A, ACVRLK3, ALK3

Chain

signal peptide:1-23, chain:24-532

Reference Genes

BioGPS Gene:657 BMPR1A

COSMIC (genes):BMPR1A BMPR1A

CTD Gene:657 BMPR1A

dbSNP Gene:657 BMPR1A

ENSEMBL:ENSG00000107779 BMPR1A

ENSEMBL_homo_sapiens_GENE:ENSG00000107779.15 BMPR1A

HGNC:1076 BMPR1A

KEGG Gene (Homo sapiens):657 BMPR1A

Monarch:657 BMPR1A

NCBI Gene:657 BMPR1A

OMIM:601299 BMPR1A

UCSC:P36894 BMPR1A

Reference Transcript

Other Identifiers

11722914_s_at

11722915_at

11722916_s_at

16706875

204832_PM_s_at

204832_s_at

213578_PM_at

213578_at

227273_PM_at

227273_at

230979_PM_at

230979_at

242731_PM_x_at

242731_x_at

2973634

2973636

2973638

2973639

2973640

2973642

2973644

2973645

3256071

3256072

3256075

3256092

3256100

3256101

3256105

3256106

3256111

3256112

3256118

3256119

3256121

3256122

3256123

3256124

3256126

3256127

3256128

3256129

3256130

3256131

3256132

3256133

3256134

3256135

3256136

3256143

3394965

3394967

3394968

3394969

3394970

39565_at

58485_at

61079_at

65688_at

657

7928855

7952305

80703_at

A_19_P00803411

A_19_P00804767

A_19_P00805548

A_23_P1431

A_24_P527404

A_33_P3219256

GE507477

GE60368

GO:0000166

GO:0001525

GO:0001649

GO:0001701

GO:0001707

GO:0001756

GO:0001880

GO:0002053

GO:0002062

GO:0002376

GO:0003007

GO:0003148

GO:0003151

GO:0003161

GO:0003171

GO:0003183

GO:0003186

GO:0003203

GO:0003215

GO:0003222

GO:0003223

GO:0003272

GO:0003824

GO:0004672

GO:0004674

GO:0004675

GO:0005025

GO:0005515

GO:0005524

GO:0005886

GO:0005901

GO:0006351

GO:0006355

GO:0006468

GO:0006955

GO:0007178

GO:0007179

GO:0007389

GO:0007398

GO:0007399

GO:0007492

GO:0007507

GO:0009897

GO:0009950

GO:0009952

GO:0009953

GO:0009986

GO:0010604

GO:0010628

GO:0010629

GO:0014032

GO:0014912

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0021953

GO:0021983

GO:0021998

GO:0022414

GO:0023052

GO:0030154

GO:0030324

GO:0030425

GO:0030501

GO:0030509

GO:0032915

GO:0035019

GO:0035137

GO:0035912

GO:0036122

GO:0036211

GO:0042475

GO:0042733

GO:0042803

GO:0043025

GO:0043167

GO:0043235

GO:0045669

GO:0045944

GO:0046332

GO:0046872

GO:0048339

GO:0048352

GO:0048368

GO:0048378

GO:0048382

GO:0048568

GO:0048589

GO:0048598

GO:0048856

GO:0048870

GO:0050673

GO:0050679

GO:0050768

GO:0051148

GO:0051173

GO:0051216

GO:0051239

GO:0060021

GO:0060043

GO:0060045

GO:0060089

GO:0060391

GO:0060412

GO:0060896

GO:0060914

GO:0060928

GO:0061626

GO:0071363

GO:0071773

GO:0080090

GO:0098802

GO:0098821

GO:0140096

GO:1902895

GO:1904414

GO:1904707

GO:1905285

GO:1990712

GO:2000772

HMNXSV003017063

Hs.150647.0.A1_3p_at

Hs.155764.0.S1_3p_at

Hs.323099.0.A1_3p_at

ILMN_1706957

ILMN_2095577

PH_hs_0027543

TC10000609.hg

TC11002378.hg

Z22535_at

g4757853_3p_a_at

Participates

as a member of

p-4S-BMPRI [plasma membrane] (Homo sapiens)

Other forms of this molecule

BMPR1A [plasma membrane]

Inferred To

phospho-BMPR1A [plasma membrane] (Canis familiaris)

phospho-BMPR1A [plasma membrane] (Gallus gallus)

phospho-p-4S-BMPR1A [plasma membrane] (Bos taurus)

phospho-p-4S-BMPR1A [plasma membrane] (Caenorhabditis elegans)

phospho-p-4S-BMPR1A [plasma membrane] (Danio rerio)

phospho-p-4S-BMPR1A [plasma membrane] (Drosophila melanogaster)

phospho-p-4S-BMPR1A [plasma membrane] (Mus musculus)

phospho-p-4S-BMPR1A [plasma membrane] (Rattus norvegicus)

phospho-p-4S-BMPR1A [plasma membrane] (Sus scrofa)

phospho-p-4S-BMPR1A [plasma membrane] (Xenopus tropicalis)

Modified Residues

Name

O-phospho-L-serine at 215

Coordinate

215

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 216

Coordinate

216

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 218

Coordinate

218

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 220

Coordinate

220

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

XP_011538406.1, NP_004320.2, XP_011538405.1

ZINC - World Drugs

BMR1A_HUMAN

Guide to Pharmacology - Targets

1786

OpenTargets

ENSG00000107779

ZINC - FDA approved

BMR1A_HUMAN

ZINC - Substances

BMR1A_HUMAN

ZINC target

P36894

ZINC - Biogenic

BMR1A_HUMAN

PRO

P36894

PDB

2H64, 3QB4, 2K3G, 1REW, 2GOO, 2QJ9, 2QJA, 3NH7, 1ES7, 2H62, 2QJB

HPA

ENSG00000107779-BMPR1A

GeneCards

P36894

Ensembl

ENSP00000490273, ENST00000636056, ENSP00000492290, ENST00000635816, ENST00000372037, ENSP00000489707, ENSG00000107779, ENSP00000361107, ENST00000638429

Pharos - Targets

P36894

Orphanet

15372

ZINC - Predictions - Purchasable

BMR1A_HUMAN

HMDB Protein

HMDBP01209

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P12644 BMP4	4	BMP4(20-408) [extracellular region] (R-HSA-2396280) BMP4 [extracellular region] (R-HSA-8858573) p-BMP4 [endoplasmic reticulum lumen] (R-HSA-8956944) BMP4 [endoplasmic reticulum lumen] (R-HSA-8956775)	0.609	2

Cite Us!