FGFR1c P252X mutants [plasma membrane]

Stable Identifier
Set [DefinedSet]
Homo sapiens
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
16140923 Somatic mutations of the protein kinase gene family in human lung cancer

Easton, DF, Dicks, E, Stratton, MR, Davies, H, Cooper, CS, Tofts, C, Teh, BT, Edkins, S, Teague, J, Pierotti, MA, Futreal, PA, Webb, A, Forbes, S, Flanagan, AM, Kosmidou, V, Lakhani, SR, Laman, R, Jones, D, Knowles, M, Hinton, J, Hunter, C, Yates, A, Greenman, C, Halliday, K, Yuen, ST, Hills, K, O'Meara, S, Perry, J, Malkowicz, B, Menzies, A, Parker, A, Nicholson, AG, Clements, J, Edwards, K, Green, A, Looijenga, LH, Harrison, R, Lugg, R, Leung, SY, Butler, A, Stephens, P, Stephens, Y, Stevens, C, Cole, J, Brackenbury, L, Small, A, Brasseur, F, Smith, R, Buck, G, Solomon, H, Raine, K, Barthorpe, S, Shepherd, R, Bignell, G, Petty, R, Avis, T, Weber, BL, West, S, Widaa, S, Goldstraw, P, Gorton, M, Gray, K, Wooster, R, Varian, J

Cancer Res 2005
18056464 Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines

Tay, LS, Streit, S, Lee, TC, Ullrich, A, Loo, HL, Lim, SJ, Venkatesh, B, Foo, P, Mann, C, Luo, M, Peng, K, Wong, CH, Ong, H, Wong, W, Gaertner, S, Tay, A, Pok, S, Hart, S, Peter, S, Hoefler, H, Bezler, M, Ruhe, JE, Ho, HK, Knyazev, P, Iacobelli, S, Brenner, S, Knyazeva, T, Specht, K

Cancer Res 2007
14613973 Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke craniosynostosis syndromes through enhancement of FGF binding affinity

Eliseenkova, AV, Linhardt, RJ, Zhang, F, Mohammadi, M, Ibrahimi, OA

Hum Mol Genet 2004
Name Identifier Synonyms
lung cancer DOID:1324
melanoma DOID:1909 Naevocarcinoma, melanoma, melanoma, malignant melanoma, morphology (morphologic abnormality), malignant melanoma NOS (morphologic abnormality), malignant melanoma (disorder), malignant melanoma, malignant melanoma, malignant melanoma, malignant melanoma
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
bone development disease DOID:0080006
Pfeiffer syndrome DOID:14705 acrocephalosyndactylia type V
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