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FGFR3c P250R mutant dimer bound to FGF [plasma membrane]
Stable Identifier
R-HSA-2011952
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR3 in disease (Homo sapiens)
Signaling by FGFR3 point mutants in cancer (Homo sapiens)
FGFR3 mutant receptor activation (Homo sapiens)
FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)
FGFR3 mutant dimers [plasma membrane] (Homo sapiens)
FGFR3c P250R mutant dimer bound to FGF [plasma membrane] (Homo sapiens)
FGFR3 mutant dimers:TKIs [plasma membrane] (Homo sapiens)
FGFR3 mutant dimers [plasma membrane] (Homo sapiens)
FGFR3c P250R mutant dimer bound to FGF [plasma membrane] (Homo sapiens)
Signaling by activated point mutants of FGFR3 (Homo sapiens)
Autocatalytic phosphorylation of FGFR3c P250R mutant (Homo sapiens)
FGFR3c P250R mutant dimer bound to FGF [plasma membrane] (Homo sapiens)
FGFR3c P250R mutant binds to ligand with enhanced affinity (Homo sapiens)
FGFR3c P250R mutant dimer bound to FGF [plasma membrane] (Homo sapiens)
Participants
components
FGFR3c P250R mutant dimer [plasma membrane] (Homo sapiens)
2 x
FGFR3c-binding FGFs [extracellular region] (Homo sapiens)
HS [extracellular region]
Participant Of
input
Autocatalytic phosphorylation of FGFR3c P250R mutant
output
FGFR3c P250R mutant binds to ligand with enhanced affinity
hasMember
FGFR3 mutant dimers [plasma membrane]
Disease
Name
Identifier
Synonyms
bone development disease
0080006
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