Reactome | BNIP2 [cytosol]

BNIP2 [cytosol]

Stable Identifier

R-HSA-200792

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

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Locations in the PathwayBrowser for interactor UniProt:Q53GL0 PKHO1

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External Reference Information

External Reference

UniProt:Q12982 BNIP2

Gene Names

BNIP2, NIP2

Chain

chain:1-314

Reference Genes

BioGPS Gene:663 BNIP2

COSMIC (genes):BNIP2 BNIP2

CTD Gene:663 BNIP2

dbSNP Gene:663 BNIP2

ENSEMBL:ENSG00000140299 BNIP2

ENSEMBL_homo_sapiens_GENE:ENSG00000140299.14 BNIP2

HGNC:1083 BNIP2

KEGG Gene (Homo sapiens):663 BNIP2

Monarch:663 BNIP2

NCBI Gene:663 BNIP2

OMIM:603292 BNIP2

UCSC:Q12982 BNIP2

Reference Transcript

Other Identifiers

11723670_a_at

11723671_x_at

11748298_a_at

16810040

209308_3p_s_at

209308_PM_s_at

209308_s_at

226280_PM_at

226280_at

243985_PM_at

243985_at

32060_at

3627059

3627060

3627061

3627062

3627063

3627064

3627065

3627070

3627072

3627073

3627074

3627075

3627077

3627078

3627079

3627087

3627088

3627089

3627090

3627096

3627102

3627103

3627104

3627105

3627108

3627109

64034_at

663

7989323

A_33_P3227467

A_33_P3400653

GE52956

GE58958

GE735994

GO:0005096

GO:0005509

GO:0005515

GO:0005634

GO:0005635

GO:0005730

GO:0005737

GO:0005829

GO:0006915

GO:0012501

GO:0043066

GO:0043226

GO:0043231

GO:0048471

GO:0090649

GO:0098772

HMNXSV003008672

HMNXSV003012494

Hs.24052.0.A1_3p_at

Hs.279528.0.A1_3p_at

ILMN_1770803

PH_hs_0023028

PH_hs_0039982

TC15001503.hg

U15173_at

g12803290_3p_a_at

g12803290_3p_at

g12803290_3p_x_at

Participates

as an input of

Bnip2 interacts with CDO complex (Homo sapiens)

as a component of

Cadherin-catenin:CDO:BOC:Bnip2 [plasma membrane] (Homo sapiens)

Inferred To

bnip2 [cytosol] (Xenopus tropicalis)

Bnip2 [cytosol] (Mus musculus)

Bnip2 [cytosol] (Rattus norvegicus)

BNIP2 [cytosol] (Bos taurus)

BNIP2 [cytosol] (Canis familiaris)

BNIP2 [cytosol] (Gallus gallus)

BNIP2 [cytosol] (Sus scrofa)

anon-EST:Posey64 [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_004321.2, NP_001307604.1

OpenTargets

ENSG00000140299

GeneCards

Q12982

HPA

ENSG00000140299-BNIP2

Ensembl

ENSG00000140299, ENSP00000412767, ENSP00000475320, ENST00000607373, ENST00000415213

PRO

Q12982

Pharos - Targets

Q12982

Interactors (48)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42685 FRK	4	FRK [specific granule lumen] (R-HSA-6801037) FRK [extracellular region] (R-HSA-6806235) FRK [azurophil granule lumen] (R-HSA-6799142) p-Y387-FRK [cytosol] (R-HSA-8847965)	0.83	8
UniProt:Q969F0 FATE1			0.718	6
UniProt:Q9NUM3 S39A9			0.556	3
UniProt:Q6ZPD8 DGAT2L6	1	DGAT2L6 [endoplasmic reticulum membrane] (R-HSA-8848588)	0.556	3
UniProt:Q96LJ7 DHRS1			0.556	3
UniProt:Q92520 FAM3C	2	FAM3C [extracellular region] (R-HSA-8848922) FAM3C [platelet dense granule lumen] (R-HSA-8848884)	0.556	3
UniProt:Q5T700 LRAD1			0.556	3
UniProt:H3BQL7 H3BQL7			0.556	3
UniProt:O95562 SFT2B			0.556	3
UniProt:Q9H9P2 CHODL			0.556	3
UniProt:O75477 ERLIN1	1	ERLIN1 [endoplasmic reticulum membrane] (R-HSA-8866518)	0.556	3
UniProt:Q53GL0 PKHO1			0.556	3
UniProt:Q9BSY9 DESI2			0.556	3
UniProt:P0C671 BNIP5			0.556	3
UniProt:Q8TDT2 GP152			0.556	3
UniProt:Q6P587-2 FAHD1			0.556	3
UniProt:B2R9H7 B2R9H7			0.556	3
UniProt:P21579 SYT1	7	SYT1 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869113) SYT1 [synaptic vesicle membrane] (R-HSA-194789) SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane] (R-HSA-210536) SYT1 [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-372514) SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917741) SYT1 [plasma membrane] (R-HSA-168786) SYT1 [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-372508)	0.556	3
UniProt:P32243-2 OTX2			0.556	3
UniProt:Q9Y320 TMX2			0.556	3
UniProt:Q12983 BNIP3			0.556	3
UniProt:Q9UH17-2 Q9UH172			0.556	3
UniProt:Q8TBB6 S7A14			0.556	3
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.556	3
UniProt:Q9H400 LIME1			0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:Q9ULV0 MYO5B	1	MYO5B [cytoplasmic vesicle membrane] (R-HSA-2028712)	0.556	5
UniProt:Q7Z769 S35E3			0.556	3
UniProt:Q07866-2 KLC1			0.556	3
UniProt:O00623 PEX12	2	PEX12 [cytosol] (R-HSA-9603782) PEX12 [peroxisomal membrane] (R-HSA-8953911)	0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:Q8TB40 ABHD4	1	ABHD4 [endoplasmic reticulum membrane] (R-HSA-5694582)	0.556	3
UniProt:Q8IUY3 GRM2A			0.556	3
UniProt:Q8N9I0 SYT2	3	SYT2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869116) SYT2 [plasma membrane] (R-HSA-168795) SYT2 [synaptic vesicle membrane] (R-HSA-194786)	0.556	3
UniProt:O15499 GSC2			0.556	3
UniProt:P50221 MEOX1			0.556	3
UniProt:O15393-2 TMPRSS2			0.556	3
UniProt:Q9NRZ7 AGPAT3	2	AGPAT3 [Golgi membrane] (R-HSA-8849239) AGPAT3 [endoplasmic reticulum membrane] (R-HSA-61807)	0.556	3
UniProt:Q9ULV0-2 MYO5B			0.556	3
UniProt:P00387 CYB5R3	3	MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (R-HSA-198771) CYB5R3(27-301) [extracellular region] (R-HSA-6806205) CYB5R3(27-301) [azurophil granule lumen] (R-HSA-6799217)	0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:O14681 EI24			0.556	3
UniProt:Q8TDF6-2 RASGRP4			0.556	3
UniProt:Q7Z7G2 CPLX4			0.556	3
UniProt:Q96Q45-2 TMEM237			0.556	3
UniProt:O95279 KCNK5	1	KCNK5 [plasma membrane] (R-HSA-1296323)	0.556	3
UniProt:Q5T7V8 GORAB			0.556	3
UniProt:Q07866 KLC1	3	KLC1(1-420)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711978) KLC1(1-420)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711968) KLC1 [cytosol] (R-HSA-983284)	0.556	3

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