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HMHA1 [cytosol]
Stable Identifier
R-HSA-200621
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
HMHA1 [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GAPs stimulate RAC1 GTPase activity (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
HMHA1 [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GAPs stimulate RHOA GTPase activity (Homo sapiens)
RHOA GAPs [cytosol] (Homo sapiens)
HMHA1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92619 HMHA1
Gene Names
HMHA1, KIAA0223, ARHGAP45
Chain
chain:1-1136, peptide:137-145
Reference Genes
BioGPS Gene:23526 HMHA1
CTD Gene:23526 HMHA1
dbSNP Gene:23526 HMHA1
ENSEMBL:ENSG00000180448 HMHA1
ENSEMBL_homo_sapiens_GENE:ENSG00000180448.11 HMHA1
HGNC:17102 HMHA1
KEGG Gene (Homo sapiens):23526 HMHA1
Monarch:23526 HMHA1
NCBI Gene:23526 HMHA1
OMIM:601155 HMHA1
UCSC:Q92619 HMHA1
Reference Transcript
RefSeq:NM_001282335.1 HMHA1
RefSeq:NM_001258328.2 HMHA1
RefSeq:NM_012292.4 HMHA1
RefSeq:NM_001282334.1 HMHA1
Other Identifiers
11723537_a_at
11747019_a_at
11747020_x_at
11749002_a_at
11749104_x_at
16856421
212873_PM_at
212873_at
23526
33748_at
3815495
3815496
3815500
3815501
3815503
3815504
3815505
3815506
3815507
3815508
3815509
3815510
3815512
3815513
3815514
3815515
3815516
3815517
3815518
3815520
3815521
3815522
3815524
3815525
3815526
3815527
3815529
3815530
8024170
A_33_P3318414
D86976_at
GE62604
GO:0005096
GO:0005515
GO:0005576
GO:0005737
GO:0005764
GO:0005773
GO:0005829
GO:0005886
GO:0007165
GO:0016020
GO:0023052
GO:0031410
GO:0032587
GO:0034774
GO:0035578
GO:0042995
GO:0043226
GO:0046872
GO:0051056
GO:0098772
HMNXSV003047860
Hs.196914.0.A1_3p_at
ILMN_1811392
PH_hs_0011617
TC19000029.hg
p33689
Participates
as a member of
RHOA GAPs [cytosol] (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
Other forms of this molecule
HMHA1 [azurophil granule lumen]
HMHA1 [extracellular region]
HMHA1 [secretory granule lumen]
Inferred To
SAC7 [cytosol]
(Saccharomyces cerevisiae)
rga5 [cytosol]
(Schizosaccharomyces pombe)
ARHGAP45 [cytosol]
(Bos taurus)
ARHGAP45 [cytosol]
(Canis familiaris)
ARHGAP45 [cytosol]
(Sus scrofa)
Arhgap45 [cytosol]
(Mus musculus)
Arhgap45 [cytosol]
(Rattus norvegicus)
spv-1 [cytosol]
(Caenorhabditis elegans)
HMHA1 [cytosol]
(Gallus gallus)
Cross References
RefSeq
NP_036424.2
,
NP_001269264.1
,
NP_001269263.1
,
NP_001245257.1
GeneCards
Q92619
HPA
ENSG00000180448-ARHGAP45
Ensembl
ENSG00000180448
,
ENST00000539243
,
ENSP00000316772
,
ENST00000313093
,
ENSP00000439601
PRO
Q92619
Pharos - Targets
Q92619
HMDB Protein
HMDBP10953
PDB
3FT3
,
3D25
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63000 RAC1
6
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
RAC1 [secretory granule membrane]
(R-HSA-6804770)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [cytosol]
(R-HSA-442615)
RAC1 [plasma membrane]
(R-HSA-351141)
0.571
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
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