Reactome | CPT2 converts palmitoyl carnitine to palmitoyl-CoA

CPT2 converts palmitoyl carnitine to palmitoyl-CoA

Stable Identifier

R-HSA-200410

Type

Reaction [transition]

Species

Homo sapiens

Compartment

mitochondrial inner membrane, mitochondrial matrix

Synonyms

palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

CPT2 converts palmitoyl carnitine to palmitoyl-CoA

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

CPT2, associated with the inner mitochondrial membrane, catalyzes the reaction of palmitoylcarnitine and CoASH to form palmitoyl-CoA and carnitine (Verderio et al. 1995; Violante et al. 2010).

Literature References

PubMed ID	Title	Journal	Year
20538056	Carnitine palmitoyltransferase 2: New insights on the substrate specificity and implications for acylcarnitine profiling IJlst, L, Violante, S, Wanders, RJA, de Almeida, IT, Ventura, FV, Van Lenthe, H	Biochim Biophys Acta	2010
7711730	Carnitine palmitoyltransferase II deficiency: structure of the gene and characterization of two novel disease-causing mutations Taroni, F, DiDonato, S, Verderio, E, Lamantea, E, Finocchiaro, G, Cavadini, P, Gellera, C, Wang, H, Montermini, L	Hum Mol Genet	1995