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CKMT1A [mitochondrial inner membrane]
Stable Identifier
R-HSA-200361
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
CKMT1A,B, Creatine kinase, ubiquitous
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Creatine metabolism (Homo sapiens)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Homo sapiens)
CK octamers [mitochondrial inner membrane] (Homo sapiens)
creatine kinase, ubiquitous, octamer [mitochondrial inner membrane] (Homo sapiens)
CKMT1A [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12532 CKMT1A
Gene Names
CKMT1A, CKMT, CKMT1B, CKMT
Chain
transit peptide:1-39, chain:40-417
Reference Genes
BioGPS Gene:1159 CKMT1A
BioGPS Gene:548596 CKMT1A
COSMIC (genes):CKMT1A CKMT1A
COSMIC (genes):CKMT1B CKMT1A
CTD Gene:1159 CKMT1A
CTD Gene:548596 CKMT1A
dbSNP Gene:1159 CKMT1A
dbSNP Gene:548596 CKMT1A
ENSEMBL:ENSG00000223572 CKMT1A
ENSEMBL:ENSG00000237289 CKMT1A
HGNC:1995 CKMT1A
HGNC:31736 CKMT1A
KEGG:hsa:1159 CKMT1A
KEGG:hsa:548596 CKMT1A
Monarch:1159 CKMT1A
Monarch:548596 CKMT1A
NCBI Gene:1159 CKMT1A
NCBI Gene:548596 CKMT1A
OMIM:123290 CKMT1A
OMIM:613415 CKMT1A
UCSC:P12532 CKMT1A
Reference Transcript
RefSeq:XM_017022369.1 CKMT1A
RefSeq:XM_017022370.1 CKMT1A
RefSeq:NM_001321927.1 CKMT1A
RefSeq:NM_001321928.1 CKMT1A
RefSeq:XM_011521194.1 CKMT1A
RefSeq:XM_011521196.1 CKMT1A
RefSeq:XM_011521195.2 CKMT1A
RefSeq:NM_001015001.2 CKMT1A
RefSeq:NM_001321926.1 CKMT1A
RefSeq:NM_020990.4 CKMT1A
RefSeq:XM_011521197.2 CKMT1A
Other Identifiers
1159
11717916_s_at
11747744_s_at
11760204_x_at
11760991_a_at
11761010_a_at
11761722_x_at
11762272_x_at
16800242
16800268
202712_PM_s_at
202712_s_at
31887_at
3591511
3591512
3591514
3591515
3591516
3591517
3591518
3591519
3591520
3591521
3591522
3591523
3591524
3591525
3591526
3591527
3591528
3591529
3591530
3591531
3591532
3591533
3591534
3591536
3591537
3591538
3591540
3591543
3591563
3591564
3591565
3591566
3591567
3591568
3591569
3591570
3591571
3591572
3591573
3591574
3591575
3591576
3591577
3591578
3591579
3591580
3591581
3591582
3591583
3591584
3591585
3591587
3591590
3591591
3591592
3591597
3591599
3591600
548596
70362_at
7983239
7983256
A_14_P116552
A_23_P163227
A_23_P163235
A_24_P339024
A_33_P3316348
GE57508
GO:0003824
GO:0004111
GO:0005515
GO:0005524
GO:0005739
GO:0005743
GO:0006575
GO:0016301
GO:0016740
GO:0016772
GO:0043226
GO:0046314
HMNXSV003027956
HMNXSV003051334
ILMN_1715476
ILMN_1732066
ILMN_1763491
J04469_at
PH_hs_0030145
PH_hs_0039435
TC15002176.hg
TC15002758.hg
TC15002759.hg
g11641403_3p_s_at
p5539
Participates
as a component of
creatine kinase, ubiquitous, octamer [mitochondrial inner membrane] (Homo sapiens)
Inferred To
CKMT1A [mitochondrial inner membrane]
(Bos taurus)
CKMT1A [mitochondrial inner membrane]
(Canis familiaris)
CKMT1A [mitochondrial inner membrane]
(Danio rerio)
CKMT1A [mitochondrial inner membrane]
(Gallus gallus)
CKMT1A [mitochondrial inner membrane]
(Mus musculus)
CKMT1A [mitochondrial inner membrane]
(Rattus norvegicus)
CKMT1A [mitochondrial inner membrane]
(Sus scrofa)
CKMT1A [mitochondrial inner membrane]
(Xenopus tropicalis)
Cross References
OpenTargets
ENSG00000223572
,
ENSG00000237289
ENSEMBL
ENSP00000406577
,
ENSP00000300283
,
ENST00000434505
,
ENSG00000223572
,
ENST00000300283
,
ENSG00000237289
,
ENSP00000413255
,
ENSP00000413165
,
ENST00000413453
,
ENST00000441322
IntEnz
2.7.3.2
HPA
ENSG00000223572-CKMT1A
,
ENSG00000237289-CKMT1B
GeneCards
CKMT1A
,
CKMT1B
PRO
P12532
Pharos - Targets
P12532
GlyGen
P12532
PDB
1QK1
HMDB Protein
HMDBP00721
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17980 PSMC3
5
PSMC3 [cytosol]
(R-HSA-68774)
PSMC3 [nucleoplasm]
(R-HSA-174313)
PSMC3 [ficolin-1-rich granule lumen]
(R-HSA-6800429)
PSMC3 [extracellular region]
(R-HSA-6806496)
PSMC3 [secretory granule lumen]
(R-HSA-6800917)
0.556
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:O00429 DNM1L
2
DNM1L [cytosol]
(R-HSA-351943)
DNM1L [mitochondrial outer membrane]
(R-HSA-351942)
0.527
3
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.527
4
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
6
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