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TLL2 [extracellular region]
Stable Identifier
R-HSA-2002461
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Tolloid-like protein 2, TLL2_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Anchoring fibril formation (Homo sapiens)
Cleavage of collagen VII NC2 region by BMP1 (Homo sapiens)
Collagen type VII NC2 proteinases [extracellular region] (Homo sapiens)
TLL2 [extracellular region] (Homo sapiens)
Crosslinking of collagen fibrils (Homo sapiens)
Prolysyl oxidase activation (Homo sapiens)
Procollagen C-proteinases [extracellular region] (Homo sapiens)
TLL2:PCPE1 [extracellular region] (Homo sapiens)
TLL2 [extracellular region] (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Removal of fibrillar collagen C-propeptides (Homo sapiens)
Procollagen C-proteinases [extracellular region] (Homo sapiens)
TLL2:PCPE1 [extracellular region] (Homo sapiens)
TLL2 [extracellular region] (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1 (Homo sapiens)
BMP1, TLL1, TLL2, Cathepsin L1 [extracellular region] (Homo sapiens)
TLL2 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y6L7 TLL2
Gene Names
TLL2, KIAA0932
Chain
signal peptide:1-25, propeptide:26-149, chain:150-1015
Reference Genes
BioGPS Gene:7093 TLL2
COSMIC (genes):TLL2 TLL2
CTD Gene:7093 TLL2
dbSNP Gene:7093 TLL2
ENSEMBL:ENSG00000095587 TLL2
HGNC:11844 TLL2
Monarch:7093 TLL2
NCBI Gene:7093 TLL2
OMIM:606743 TLL2
UCSC:Q9Y6L7 TLL2
Reference Transcript
RefSeq:NM_012465.3 TLL2
Other Identifiers
11735133_at
11735134_a_at
11735135_at
11735136_at
16716956
208027_PM_s_at
208027_s_at
215008_PM_at
215008_at
215843_PM_s_at
215843_s_at
3301801
3301802
3301803
3301804
3301805
3301806
3301807
3301808
3301810
3301811
3301813
3301816
3301820
3301822
3301824
3301825
3301826
3301827
3301828
3301830
3301832
3301835
3301837
3301838
3301845
3301846
3301855
3301856
36343_at
7093
7935296
A_23_P404778
A_23_P436158
GE539154
GO:0003824
GO:0004222
GO:0004252
GO:0005509
GO:0005576
GO:0005615
GO:0006508
GO:0008237
GO:0008270
GO:0009953
GO:0016485
GO:0016787
GO:0030154
GO:0030198
GO:0030199
GO:0046872
GO:0048632
GO:0051604
GO:0140096
HMNXSV003005359
HMNXSV003028074
Hs.154296.0.S1_3p_at
Hs.287695.0.S1_3p_s_at
ILMN_1755158
ILMN_2206307
PH_hs_0009289
TC10001557.hg
g6912723_3p_s_at
p1711
Participates
as a member of
Collagen type VII NC2 proteinases [extracellular region] (Homo sapiens)
BMP1, TLL1, TLL2, Cathepsin L1 [extracellular region] (Homo sapiens)
as a component of
TLL2:PCPE1 [extracellular region] (Homo sapiens)
Inferred To
TLL2 [extracellular region]
(Bos taurus)
TLL2 [extracellular region]
(Caenorhabditis elegans)
TLL2 [extracellular region]
(Canis familiaris)
TLL2 [extracellular region]
(Drosophila melanogaster)
TLL2 [extracellular region]
(Mus musculus)
TLL2 [extracellular region]
(Rattus norvegicus)
TLL2 [extracellular region]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000350630
,
ENST00000357947
OpenTargets
ENSG00000095587
HPA
ENSG00000095587-TLL2
PRO
Q9Y6L7
Pharos - Targets
Q9Y6L7
GlyGen
Q9Y6L7
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