CD19 is a lymphocyte cell surface molecule that functions as a general response regulator or rheostat, which defnes signalling thresholds. These responses are infuenced by signals transduced through a CD19-CD21 cell surface receptor complex, where the binding of complement C3d to CD21 links humoral immune responses with the innate immune system. The CD19-CD21 complex is composed of at least four non-covalently associated proteins: CD19, CD21(complement receptor 2),CD81 and CD225.
Del Nagro, CJ, Otero, DC, Anzelon, AN, Omori, SA, Kolla, RV, Rickert, RC
Toapanta, FR, Ross, TM
Carter, RH, Barrington, RA
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