FABP1 [nucleoplasm]

Stable Identifier
R-HSA-1989743
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Fatty acid-binding protein, liver, FABPL_HUMAN
Icon
FABP1 [nucleoplasm] icon
FABP1 [nucleoplasm] icon
Locations in the PathwayBrowser for interactor UniProt:FLNA
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General

As inferred from mouse, FABP1 localizes to the nucleus where it may deliver lipids to PPARA.

Literature References
PubMed ID Title Journal Year
19289416 L-FABP directly interacts with PPARalpha in cultured primary hepatocytes

Hostetler, HA, McIntosh, AL, Atshaves, BP, Storey, SM, Payne, HR, Kier, AB, Schroeder, F

J Lipid Res 2009
11226238 Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus

Wolfrum, C, Borrmann, CM, Borchers, T, Spener, F

Proc Natl Acad Sci U S A 2001
External Reference Information
External Reference
UniProt:P07148 FABP1
Gene Names
FABP1, FABPL
Chain
chain:1-127
Reference Genes
BioGPS Gene:2168 FABP1
COSMIC (genes):FABP1 FABP1
CTD Gene:2168 FABP1
dbSNP Gene:2168 FABP1
ENSEMBL:ENSG00000163586 FABP1
HGNC:3555 FABP1
KEGG Gene (Homo sapiens):2168 FABP1
Monarch:2168 FABP1
NCBI Gene:2168 FABP1
OMIM:134650 FABP1
Reference Transcript
Other Identifiers
0006550025
11723040_a_at
11723041_s_at
11758878_x_at
16900030
205892_s_at
2168
2563539
2563540
2563546
2563548
2563554
2563555
38586_at
8053654
A_23_P79562
GE81021
GO:0003674
GO:0003682
GO:0005324
GO:0005504
GO:0005515
GO:0005543
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005777
GO:0005782
GO:0005829
GO:0006629
GO:0006810
GO:0006950
GO:0008144
GO:0008150
GO:0008219
GO:0008289
GO:0009056
GO:0015909
GO:0016209
GO:0019216
GO:0019433
GO:0032000
GO:0032052
GO:0032991
GO:0043066
GO:0043154
GO:0043167
GO:0043226
GO:0044281
GO:0045179
GO:0050892
GO:0051345
GO:0070062
GO:0070301
GO:0071456
GO:0098869
ILMN_1678965
ILMN_1772328
M10050_at
PH_hs_0018467
TC02002069.hg
TC02004392.hg
g4557576_3p_at
g4557576_3p_s_at
Participant Of
output
hasComponent
Other forms of this molecule
FABP1 [cytosol]
Inferred To
Fabp1 [nucleoplasm] (Mus musculus)
Fabp1 [nucleoplasm] (Rattus norvegicus)
fabp [nucleoplasm] (Drosophila melanogaster)
cytl1 [nucleoplasm] (Xenopus tropicalis)
fabp1b.1 [nucleoplasm] (Danio rerio)
FABP1 [nucleoplasm] (Bos taurus)
FABP1 [nucleoplasm] (Canis familiaris)
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
ZINC target
PRO
PDB
Interactors (2)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P21333-2 FLNA      0.556 3
 UniProt:FLNA Q5HY54      0.556 3
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