FABP1 [nucleoplasm]

Stable Identifier
R-HSA-1989743
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Fatty acid-binding protein, liver, FABPL_HUMAN
FABP1 [nucleoplasm] icon
Locations in the PathwayBrowser
General

As inferred from mouse, FABP1 localizes to the nucleus where it may deliver lipids to PPARA.

Literature References
PubMed ID Title Journal Year
11226238 Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus

Borrmann, CM, Wolfrum, C, Borchers, T, Spener, F

Proc Natl Acad Sci U S A 2001
19289416 L-FABP directly interacts with PPARalpha in cultured primary hepatocytes

Payne, HR, Storey, SM, Hostetler, HA, Schroeder, F, Kier, AB, McIntosh, AL, Atshaves, BP

J Lipid Res 2009
External Reference Information
External Reference
Gene Names
FABP1, FABPL
Chain
chain:1-127
Reference Transcript
Other Identifiers
0006550025
11723040_a_at
11723041_s_at
11758878_x_at
16900030
205892_s_at
2168
2563539
2563540
2563546
2563548
2563554
2563555
38586_at
8053654
A_23_P79562
GE81021
GO:0003674
GO:0003682
GO:0005324
GO:0005504
GO:0005515
GO:0005543
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005777
GO:0005782
GO:0005829
GO:0006629
GO:0006810
GO:0006950
GO:0008150
GO:0008219
GO:0008289
GO:0009056
GO:0015909
GO:0016209
GO:0019216
GO:0019222
GO:0019433
GO:0032000
GO:0032052
GO:0032991
GO:0034641
GO:0036094
GO:0042167
GO:0043066
GO:0043154
GO:0043167
GO:0043226
GO:0044281
GO:0045179
GO:0050892
GO:0051345
GO:0070062
GO:0070301
GO:0071456
GO:0098869
HMNXSV003007276
ILMN_1678965
ILMN_1772328
M10050_at
PH_hs_0018467
TC02002069.hg
TC02004392.hg
g4557576_3p_at
g4557576_3p_s_at
Participates
Other forms of this molecule
Inferred To
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
GeneCards
ZINC target
PRO
Pharos - Targets
Interactors (2)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P21333-2 FLNA      0.556 3
 UniProt:FLNA Q5HY54      0.556 3
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