Reactome | MyrG-CYB5R3(2-301) [mitochondrial outer membrane]

MyrG-CYB5R3(2-301) [mitochondrial outer membrane]

Stable Identifier

R-HSA-198771

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

CYB5R3, NADH-cytochrome b5 reductase , B5R

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P00387 CYB5R3

Gene Names

CYB5R3, DIA1

Chain

initiator methionine:, chain:2-301

Reference Genes

BioGPS Gene:1727 CYB5R3

COSMIC (genes):CYB5R3 CYB5R3

CTD Gene:1727 CYB5R3

dbSNP Gene:1727 CYB5R3

ENSEMBL:ENSG00000100243 CYB5R3

HGNC:2873 CYB5R3

KEGG:hsa:1727 CYB5R3

Monarch:1727 CYB5R3

NCBI Gene:1727 CYB5R3

OMIM:613213 CYB5R3

UCSC:P00387 CYB5R3

Reference Transcript

Other Identifiers

11715554_a_at

11715555_a_at

1554574_3p_a_at

1554574_PM_a_at

1554574_a_at

16935669

1727

201885_PM_s_at

201885_s_at

36668_at

3962525

3962527

3962529

3962531

3962532

3962533

3962534

3962535

3962536

3962537

3962538

3962539

3962540

3962541

3962542

3962543

3962544

3962545

3962546

3962547

3962548

3962549

3962550

3962551

3962552

3962553

3962555

3962556

3962557

3962559

8076481

A_23_P502224

A_24_P100277

A_24_P378958

GE79690

GO:0003013

GO:0003824

GO:0004128

GO:0005515

GO:0005576

GO:0005737

GO:0005739

GO:0005741

GO:0005783

GO:0005789

GO:0005811

GO:0005829

GO:0005833

GO:0006629

GO:0006695

GO:0006809

GO:0008015

GO:0016020

GO:0016208

GO:0016491

GO:0031966

GO:0035578

GO:0043226

GO:0043531

GO:0050421

GO:0050660

GO:0051287

GO:0071949

GO:1903958

HMNXSV003013106

Hs2.274464.3.S1_3p_s_at

ILMN_1740441

ILMN_2308582

M28713_at

PH_hs_0014170

TC22000850.hg

g6552326_3p_a_at

Participates

as a component of

Other forms of this molecule

CYB5R3(27-301) [azurophil granule lumen]

CYB5R3(27-301) [extracellular region]

Inferred To

Ghost homologue of MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Caenorhabditis elegans)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Bos taurus)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Canis familiaris)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Danio rerio)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Dictyostelium discoideum)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Drosophila melanogaster)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Gallus gallus)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Mus musculus)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Rattus norvegicus)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Saccharomyces cerevisiae)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Schizosaccharomyces pombe)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Sus scrofa)

MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (Xenopus tropicalis)

Modified Residues

Name

N-myristoylglycine at 2

Coordinate

PsiMod Name

N-myristoylglycine [MOD:00068]

PsiMod Definition

A protein modification that effectively converts a glycine residue to N-myristoylglycine.

Cross References

OpenTargets

ENSG00000100243

ENSEMBL

ENST00000687198, ENSP00000508492, ENST00000352397, ENST00000407623, ENSP00000384834, ENST00000402438, ENST00000688117, ENSP00000385679, ENSP00000338461, ENSP00000509015, ENST00000692152, ENSP00000509317

HPA

ENSG00000100243-CYB5R3

ZINC - Substances

NB5R3_HUMAN

ZINC target

P00387

PRO

P00387

Pharos - Targets

P00387

Orphanet

CYB5R3

GlyGen

P00387

HMDB Protein

HMDBP00125

PDB

7TSW, 7TNV, 7THG, 7W3O, 1UMK

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.564	2
UniProt:Q7Z5P4 HSD17B13	1	HSD17B13 [cytosol] (R-HSA-8862029)	0.556	3
UniProt:O95406 CNIH1	3	CNIH1 [endoplasmic reticulum membrane] (R-HSA-5689439) CNIH1 [ER to Golgi transport vesicle membrane] (R-HSA-5689776) CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689778)	0.556	3
UniProt:Q12982 BNIP2	1	BNIP2 [cytosol] (R-HSA-200792)	0.556	3
UniProt:Q12893 TMEM115	1	TMEM115 [Golgi membrane] (R-HSA-6808815)	0.556	3
UniProt:Q8WWT9 SLC13A3	1	SLC13A3 [plasma membrane] (R-HSA-433095)	0.556	3
UniProt:Q14973 SLC10A1	1	SLC10A1 [plasma membrane] (R-HSA-194116)	0.556	3
UniProt:Q9Y5Z9 UBIAD1	1	UBIAD1 [endoplasmic reticulum membrane] (R-HSA-2980965)	0.556	3
UniProt:Q14508 WFDC2	1	WFDC2 [extracellular region] (R-HSA-9830363)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:P01350 GAST	1	GAST(76-92) [extracellular region] (R-HSA-870266)	0.556	3
UniProt:Q9BVK2 ALG8	5	ALG8 G275D [endoplasmic reticulum membrane] (R-HSA-4724304) ALG8 T47P [endoplasmic reticulum membrane] (R-HSA-4724334) ALG8 V133Sfs3 [endoplasmic reticulum membrane] (R-HSA-4724313) ALG8 T138Kfs19 [endoplasmic reticulum membrane] (R-HSA-4724312) ALG8 [endoplasmic reticulum membrane] (R-HSA-449640)	0.556	3
UniProt:P01375 TNF	5	TNF(1-233) [plasma membrane] (R-HSA-66220) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(52-76) [extracellular region] (R-HSA-8863375)	0.556	3
UniProt:O75379 VAMP4	4	VAMP4 [transport vesicle] (R-HSA-6811023) VAMP4 [trans-Golgi network membrane] (R-HSA-6811021) VAMP4 [plasma membrane] (R-HSA-8864461) VAMP4 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869133)	0.556	3

Cite Us!