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ERK5 translocates to the nucleus
Stable Identifier
R-HSA-198714
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
,
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Signalling to ERK5 (Homo sapiens)
ERK5 translocates to the nucleus (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
On phosphorylation, ERK5 translocates to the nucleus (Watson et al. 2001).
Literature References
PubMed ID
Title
Journal
Year
11544482
Neurotrophins use the Erk5 pathway to mediate a retrograde survival response
Segal, RA
,
Lin, MZ
,
Klesse, L
,
Bhattacharyya, A
,
Watson, FL
,
Heerssen, HM
Nat Neurosci
2001
Participants
Input
p-T218,Y221-MAPK7 [cytosol]
(Homo sapiens)
Output
p-T218,Y221-MAPK7 [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Signalling to ERK5 (Homo sapiens)
Orthologous Events
ERK5 translocates to the nucleus (Bos taurus)
ERK5 translocates to the nucleus (Caenorhabditis elegans)
ERK5 translocates to the nucleus (Canis familiaris)
ERK5 translocates to the nucleus (Dictyostelium discoideum)
ERK5 translocates to the nucleus (Gallus gallus)
ERK5 translocates to the nucleus (Mus musculus)
ERK5 translocates to the nucleus (Plasmodium falciparum)
ERK5 translocates to the nucleus (Rattus norvegicus)
ERK5 translocates to the nucleus (Saccharomyces cerevisiae)
ERK5 translocates to the nucleus (Schizosaccharomyces pombe)
ERK5 translocates to the nucleus (Sus scrofa)
Authored
Nasi, S (2006-10-10)
Annibali, D (2006-10-10)
Reviewed
Greene, LA (2007-11-08)
Created
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