Reactome | p-T,Y MAPK dimers [nucleoplasm]

p-T,Y MAPK dimers [nucleoplasm]

Stable Identifier

R-HSA-198701

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Phospho-ERK dimer

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional regulation by RUNX2 (Homo sapiens)
      - RUNX2 regulates bone development (Homo sapiens)
        
        RUNX2 regulates osteoblast differentiation (Homo sapiens)
        
        Activated ERKs phosphorylate RUNX2 (Homo sapiens)
        
        p-T,Y MAPK dimers [nucleoplasm] (Homo sapiens)

Participants

members

Participates

as an output of

p-T,Y MAPK dimers translocate to nucleus (Homo sapiens)

as a member of

p-T,Y MAPK monomers and dimers [nucleoplasm] (Homo sapiens)

This entity regulates

Negatively

ERF binds ETS2 promoter (Homo sapiens)

Positively

RAS signaling and prolonged interferon-beta stimulation promote generation of reactive oxygen species (ROS) (Homo sapiens)

Inferred To

p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)

p-T,Y MAPK dimers [nucleoplasm] (Caenorhabditis elegans)

p-T,Y MAPK dimers [nucleoplasm] (Canis familiaris)

p-T,Y MAPK dimers [nucleoplasm] (Dictyostelium discoideum)

p-T,Y MAPK dimers [nucleoplasm] (Mus musculus)

p-T,Y MAPK dimers [nucleoplasm] (Plasmodium falciparum)

p-T,Y MAPK dimers [nucleoplasm] (Rattus norvegicus)

p-T,Y MAPK dimers [nucleoplasm] (Saccharomyces cerevisiae)

p-T,Y MAPK dimers [nucleoplasm] (Schizosaccharomyces pombe)

p-T,Y MAPK dimers [nucleoplasm] (Sus scrofa)

p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Danio rerio)

p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Drosophila melanogaster)

p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Gallus gallus)

p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Xenopus tropicalis)

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