Phosphorylation of p27Kip1 at T157 and of p21Cip1 at T145 by AKT leads to their retention in the cytoplasm, segregating these cyclin-dependent kinase (CDK) inhibitors from cyclin-CDK complexes.
Viglietto, G, Motti, ML, Bruni, P, Melillo, RM, D'Alessio, A, Califano, D, Vinci, F, Chiappetta, G, Tsichlis, P, Bellacosa, A, Fusco, A, Santoro, M
Zhou, BP, Liao, Y, Xia, W, Spohn, B, Lee, MH, Hung, MC
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