Cytosolic malate dehydrogenase catalyzes the reaction of malate and NAD+ to form oxaloacetate and NADH + H+ (Lo et al. 2005). The dimeric structure of the human dehydrogenase is inferred from that established for its well-studied pig homolog (Birktoft et al. 1989).
Liew, C-T, Waye, MM-Y, Lee, C-Y, Tsui, SK-W, Lo, AS-Y, Ngai, S-M, Fung, K-P
L-malate dehydrogenase activity of malate dehydrogenase 1 dimer [cytosol]
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