PI3K produces PIP3 and other phosphatidyl inositides

Stable Identifier
R-HSA-198266
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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PI3-kinase phosphorylates several phosphatidyl-inositides (phospholipids) at the plasma membrane: the most relevant is PtdIns(3,4,5)P3, also named PIP3.

Literature References
PubMed ID Title Journal Year
12167717 Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

Scheid, MP, Marignani, PA, Woodgett, JR

Mol Cell Biol 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created