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PVRL4 [plasma membrane]
Stable Identifier
R-HSA-198159
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Nectin-4, Poliovirus receptor-related protein 4, Q96K15_HUMAN
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Cis-homodimerization of nectins (Homo sapiens)
Nectin [plasma membrane] (Homo sapiens)
PVRL4 [plasma membrane] (Homo sapiens)
Nectin cis-homodimer [plasma membrane] (Homo sapiens)
Nectin [plasma membrane] (Homo sapiens)
PVRL4 [plasma membrane] (Homo sapiens)
Interaction of Nectins with Afadin (Homo sapiens)
Nectin [plasma membrane] (Homo sapiens)
PVRL4 [plasma membrane] (Homo sapiens)
Nectin:afadin [plasma membrane] (Homo sapiens)
Nectin [plasma membrane] (Homo sapiens)
PVRL4 [plasma membrane] (Homo sapiens)
Nectin/Necl trans heterodimerization (Homo sapiens)
Nectin-1:Nectin-4 trans heterodimer formation (Homo sapiens)
Nectin-1:Nectin-4 trans heterodimer [cell junction] (Homo sapiens)
Nectin-4 cis homodimer [plasma membrane] (Homo sapiens)
PVRL4 [plasma membrane] (Homo sapiens)
Nectin-4 cis homodimer [plasma membrane] (Homo sapiens)
PVRL4 [plasma membrane] (Homo sapiens)
Transhomodimerization of Nectins (Homo sapiens)
Nectin cis-homodimer [plasma membrane] (Homo sapiens)
Nectin [plasma membrane] (Homo sapiens)
PVRL4 [plasma membrane] (Homo sapiens)
Nectin trans homodimer [cell junction] (Homo sapiens)
Nectin cis-homodimer [plasma membrane] (Homo sapiens)
Nectin [plasma membrane] (Homo sapiens)
PVRL4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96NY8 NECTIN4
Gene Names
NECTIN4, LNIR, PRR4, PVRL4
Chain
signal peptide:1-31, chain:32-510, chain:32-
Reference Genes
BioGPS Gene:81607 NECTIN4
COSMIC (genes):NECTIN4 NECTIN4
CTD Gene:81607 NECTIN4
dbSNP Gene:81607 NECTIN4
ENSEMBL:ENSG00000143217 NECTIN4
ENSEMBL_homo_sapiens_GENE:ENSG00000143217.9 NECTIN4
HGNC:19688 NECTIN4
KEGG Gene (Homo sapiens):81607 NECTIN4
Monarch:81607 NECTIN4
NCBI Gene:81607 NECTIN4
OMIM:609607 NECTIN4
UCSC:Q96NY8 NECTIN4
Reference Transcript
RefSeq:NM_030916.2 NECTIN4
Other Identifiers
11728764_a_at
11728765_a_at
11748451_a_at
16695558
223540_PM_at
223540_at
2440584
2440585
2440587
2440588
2440589
2440590
2440592
2440593
2440594
2440596
2440597
2440598
2440599
2440606
2440607
47385_at
7921773
81607
A_23_P46441
A_33_P3236392
GE789652
GO:0001618
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0005912
GO:0007155
GO:0007156
GO:0007157
GO:0016020
GO:0042802
GO:0043226
GO:0046718
GO:0070062
GO:0070161
HMNXSV003056555
ILMN_1749044
PH_hs_0003903
TC01003415.hg
g9049507_3p_at
Participates
as a member of
Nectin [plasma membrane] (Homo sapiens)
as a component of
Nectin-4 cis homodimer [plasma membrane] (Homo sapiens)
Inferred To
Nectin4 [plasma membrane]
(Mus musculus)
Nectin4 [plasma membrane]
(Rattus norvegicus)
igcm-3 [plasma membrane]
(Caenorhabditis elegans)
NECTIN4 [plasma membrane]
(Bos taurus)
NECTIN4 [plasma membrane]
(Canis familiaris)
NECTIN4 [plasma membrane]
(Sus scrofa)
PVRL4 [plasma membrane]
(Gallus gallus)
Fas3 [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_112178.2
Guide to Pharmacology - Targets
3112
OpenTargets
ENSG00000143217
HPA
ENSG00000143217-NECTIN4
GeneCards
Q96NY8
Ensembl
ENSP00000356991
,
ENSG00000143217
,
ENST00000368012
PRO
Q96NY8
Pharos - Targets
Q96NY8
Orphanet
19677
PDB
4FRW
,
4GJT
,
4JJH
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15223 NECTIN1
1
PVRL1 [plasma membrane]
(R-HSA-3008842)
0.756
6
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