Reactome | PLOD1 [endoplasmic reticulum membrane]

PLOD1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1981109

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1, PLOD1_HUMAN, Lysyl hydroxylase 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q02809 PLOD1

Gene Names

PLOD1, LLH, PLOD

Chain

signal peptide:1-18, chain:19-727

Reference Genes

BioGPS Gene:5351 PLOD1

COSMIC (genes):PLOD1 PLOD1

CTD Gene:5351 PLOD1

dbSNP Gene:5351 PLOD1

ENSEMBL:ENSG00000083444 PLOD1

HGNC:9081 PLOD1

KEGG:hsa:5351 PLOD1

Monarch:5351 PLOD1

NCBI Gene:5351 PLOD1

OMIM:153454 PLOD1

UCSC:Q02809 PLOD1

Reference Transcript

Other Identifiers

11715611_a_at

11749491_a_at

16659140

200827_PM_at

200827_at

2320582

2320583

2320584

2320588

2320589

2320590

2320591

2320592

2320594

2320595

2320596

2320597

2320598

2320599

2320600

2320601

2320602

2320603

2320605

2320606

2320609

2320610

2320611

2320612

2320613

2320614

2320615

2320616

2320617

2320618

36184_at

5351

7897803

A_14_P120977

A_23_P137532

A_33_P3358824

GE57569

GO:0001666

GO:0003824

GO:0005506

GO:0005515

GO:0005615

GO:0005783

GO:0005789

GO:0005794

GO:0008475

GO:0008544

GO:0016020

GO:0016491

GO:0016705

GO:0017185

GO:0030198

GO:0030199

GO:0030312

GO:0030867

GO:0031012

GO:0031418

GO:0043226

GO:0046872

GO:0048856

GO:0051213

GO:0062023

GO:0070062

GO:0140096

GO:1902494

HMNXSV003056096

ILMN_1684391

L06419_at

PH_hs_0004275

TC01000151.hg

g4557836_3p_at

Participates

as a component of

PLOD1:Fe2+ dimer [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

let-268 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

Plod1 [endoplasmic reticulum membrane] (Mus musculus)

Plod1 [endoplasmic reticulum membrane] (Rattus norvegicus)

Plod [endoplasmic reticulum membrane] (Drosophila melanogaster)

PLOD1 [endoplasmic reticulum membrane] (Bos taurus)

PLOD1 [endoplasmic reticulum membrane] (Canis familiaris)

PLOD1 [endoplasmic reticulum membrane] (Gallus gallus)

PLOD1 [endoplasmic reticulum membrane] (Sus scrofa)

plod1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001303249.1, NP_000293.2

ENSEMBL

ENST00000196061, ENSG00000083444, ENSP00000196061

OpenTargets

ENSG00000083444

GeneCards

PLOD1

HPA

ENSG00000083444-PLOD1

PRO

Q02809

Pharos - Targets

Q02809

GlyGen

Q02809

Orphanet

PLOD1

HMDB Protein

HMDBP00460

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02452 COL1A1	20	3x4Hyp-3Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023648) 3x4Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023667) GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023604) GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022999) 3x4Hyp-3Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023559) 3x4Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023582) COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1650777) 3x4Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1985659) 3x4Hyp-3Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022446) 3x4Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022951) 3x4Hyp-3Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022954) 5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1985663) Lysyl-pyrrolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396137) Lysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396440) Lysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396471) Lysyl-pyridinolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396464) Lysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396068) Lysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396388) Dehydrolysinonorlysyl 4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396315) Dehydrolysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396441)	0.643	3
UniProt:P55317 FOXA1	1	FOXA1 [nucleoplasm] (R-HSA-453074)	0.643	4
UniProt:Q9Y580 RBM7	1	RBM7 [nucleoplasm] (R-HSA-8985564)	0.527	3

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