Reactome | PLOD1 [endoplasmic reticulum membrane]

PLOD1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1981109

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1, PLOD1_HUMAN, Lysyl hydroxylase 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q02809 PLOD1

Gene Names

PLOD1, LLH, PLOD

Chain

signal peptide:1-18, chain:19-727

Reference Genes

BioGPS Gene:5351 PLOD1

COSMIC (genes):PLOD1 PLOD1

CTD Gene:5351 PLOD1

dbSNP Gene:5351 PLOD1

ENSEMBL:ENSG00000083444.17 PLOD1

HGNC:9081 PLOD1

KEGG Gene (Homo sapiens):5351 PLOD1

Monarch:5351 PLOD1

NCBI Gene:5351 PLOD1

OMIM:153454 PLOD1

UCSC:Q02809 PLOD1

Reference Transcript

Other Identifiers

0006860441

11715611_a_at

11749491_a_at

16659140

200827_PM_at

200827_at

2320583

2320584

2320589

2320590

2320591

2320592

2320594

2320597

2320598

2320600

2320601

2320602

2320603

2320605

2320606

2320609

2320610

2320612

2320613

2320615

2320616

2320617

2320618

36184_at

5351

7897803

A_14_P120977

A_23_P137532

A_33_P3358824

GE57569

GO:0001666

GO:0005506

GO:0005515

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0008475

GO:0008544

GO:0016020

GO:0016491

GO:0016705

GO:0017185

GO:0030867

GO:0031418

GO:0032991

GO:0036211

GO:0043226

GO:0046872

GO:0048856

GO:0051213

GO:0070062

GO:0140096

GO:1902494

HMNXSV003056096

ILMN_1684391

L06419_at

PH_hs_0004275

TC01000151.hg

g4557836_3p_at

Participates

as a component of

PLOD1:Fe2+ dimer [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

PLOD1 [endoplasmic reticulum membrane] (Bos taurus)

PLOD1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

PLOD1 [endoplasmic reticulum membrane] (Canis familiaris)

PLOD1 [endoplasmic reticulum membrane] (Danio rerio)

PLOD1 [endoplasmic reticulum membrane] (Drosophila melanogaster)

PLOD1 [endoplasmic reticulum membrane] (Gallus gallus)

PLOD1 [endoplasmic reticulum membrane] (Mus musculus)

PLOD1 [endoplasmic reticulum membrane] (Rattus norvegicus)

PLOD1 [endoplasmic reticulum membrane] (Sus scrofa)

plod1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_000293.2, NP_001303249.1

OpenTargets

ENSG00000083444

HPA

ENSG00000083444-PLOD1

GeneCards

Q02809

Ensembl

ENST00000196061, ENSP00000196061, ENSG00000083444

PRO

Q02809

Pharos - Targets

Q02809

Orphanet

15109

HMDB Protein

HMDBP00460

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P55317 FOXA1	1	FOXA1 [nucleoplasm] (R-HSA-453074)	0.527	2
UniProt:P02452 COL1A1	20	3x4Hyp-3Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023648) 3x4Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023667) GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023604) GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022999) 3x4Hyp-3Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023559) 3x4Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023582) COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1650777) 3x4Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1985659) 3x4Hyp-3Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022446) 3x4Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022951) 3x4Hyp-3Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022954) 5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1985663) Lysyl-pyrrolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396137) Lysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396440) Lysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396471) Lysyl-pyridinolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396464) Lysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396068) Lysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396388) Dehydrolysinonorlysyl 4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396315) Dehydrolysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396441)	0.527	2

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