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COL4A4 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-1980248
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
Collagen alpha-4(IV) chain
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type IV (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
P4HB binds Collagen chains (Homo sapiens)
Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
P4HB:Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylase procollagen substrates [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylase procollagen substrates [endoplasmic reticulum lumen] (Homo sapiens)
Collagen propeptides, chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type IV [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen alpha-3(IV), alpha-4(IV), alpha-5(IV) [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Homo sapiens)
P4HB:Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagens and tropocollagens [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type IV [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen alpha-3(IV), alpha-4(IV), alpha-5(IV) [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P53420 COL4A4
Gene Names
COL4A4
Chain
signal peptide:1-38, chain:39-1690
Reference Genes
BioGPS Gene:1286 COL4A4
COSMIC (genes):COL4A4 COL4A4
CTD Gene:1286 COL4A4
dbSNP Gene:1286 COL4A4
ENSEMBL:ENSG00000081052 COL4A4
HGNC:2206 COL4A4
KEGG Gene (Homo sapiens):1286 COL4A4
Monarch:1286 COL4A4
NCBI Gene:1286 COL4A4
OMIM:120131 COL4A4
UCSC:P53420 COL4A4
Reference Transcript
RefSeq:NM_000092.4 COL4A4
RefSeq:XM_005246281.3 COL4A4
Other Identifiers
0001990711
0104850039
11725265_at
11725266_at
1286
16909172
214602_at
229779_at
2602116
2602117
2602118
2602119
2602120
2602121
2602122
2602123
2602125
2602131
2602132
2602134
2602138
2602141
2602142
2602143
2602144
2602145
2602146
2602150
2602151
2602152
2602153
2602154
2602155
2602156
2602157
2602158
2602159
2602160
2602161
2602163
2602164
2602165
2602166
2602169
2602170
2602171
2602172
2602173
2602174
2602175
2602176
2602177
2602178
2602179
2602180
2602181
2602182
2602184
2602185
2602186
2602187
2602188
2602191
2602192
2602193
2602194
2602198
2602199
2602200
2602201
2602202
2602209
2602212
2602216
2602217
2602219
35493_at
8059477
88649_at
A_23_P254522
A_33_P3227400
D17391_at
GE87916
GO:0003674
GO:0005198
GO:0005201
GO:0005575
GO:0005576
GO:0005581
GO:0005587
GO:0005604
GO:0005615
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0008150
GO:0030020
GO:0030198
GO:0030199
GO:0031012
GO:0032836
GO:0032991
GO:0043226
GO:0048856
GO:0062023
HMNXSV003000568
HMNXSV003033888
HMNXSV003056969
Hs.119471.0.A1_3p_at
Hs.180828.0.S2_3p_at
ILMN_1778308
PH_hs_0023458
TC02002832.hg
TC02004836.hg
Participates
as a member of
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
as a candidate of
Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Collagen propeptides, chains [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
3x4Hyp-GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
GalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A4 [endoplasmic reticulum lumen]
5Hyl-COL4A4 [endoplasmic reticulum lumen]
5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
3,4-Hyp 5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
4-Hyp 5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
3x4Hyp-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-GalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-5Hyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-COL4A4(39-?) [extracellular region]
GalHyl-COL4A4(39-?) [extracellular region]
GlcGalHyl-COL4A4(?-1690) [extracellular region]
COL4A4(39-?) [extracellular region]
3x4Hyp-GalHyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4(?-1690) [extracellular region]
5Hyl-COL4A4(39-?) [extracellular region]
COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4(?-1690) [extracellular region]
5Hyl-COL4A4(?-1690) [extracellular region]
GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-5Hyl-COL4A4(39-?) [extracellular region]
3x4Hyp-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4(39-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-COL4A4(?-1690) [extracellular region]
GalHyl-COL4A4(?-1690) [extracellular region]
COL4A4(39-?) [extracellular region]
3x4Hyp-5Hyl-COL4A4 [extracellular region]
COL4A4 [extracellular region]
GalHyl-COL4A4 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4 [extracellular region]
3x4Hyp-COL4A4 [extracellular region]
5Hyl-COL4A4 [extracellular region]
3,4-Hyp Glu-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
4-Hyp 5-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
5-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
3,4-hydroxyprolyl collagen alpha-4(IV) NC1 domain [extracellular region]
Glu-Gal-Hyl-collagen alpha-4(IV) NC1 domain [extracellular region]
5-hydroxylysyl collagen alpha-4(IV) NC1 domain [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4 NC1 domain [extracellular region]
4-Hyp 5-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
3,4-Hyp 5-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
4-hydroxyprolyl collagen alpha-4(IV) NC1 domain [extracellular region]
Collagen alpha-4(IV) NC1 domain [extracellular region]
3x4Hyp-3Hyp-COL4A4 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4 [extracellular region]
GlcGalHyl-COL4A4 [extracellular region]
3x4Hyp-GalHyl-COL4A4 [extracellular region]
Inferred To
Col4a4 [endoplasmic reticulum lumen]
(Mus musculus)
Col4a4 [endoplasmic reticulum lumen]
(Rattus norvegicus)
emb-9 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
Homologues of COL4A4 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Col4a1 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
COL4A4 [endoplasmic reticulum lumen]
(Canis familiaris)
COL4A4 [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
COL4A4 [endoplasmic reticulum lumen]
(Gallus gallus)
COL4A4 [endoplasmic reticulum lumen]
(Sus scrofa)
vkg [endoplasmic reticulum lumen]
(Drosophila melanogaster)
col4a6 [endoplasmic reticulum lumen]
(Danio rerio)
col4a6 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
Cross References
RefSeq
XP_005246338.1
,
NP_000083.3
OpenTargets
ENSG00000081052
GeneCards
P53420
HPA
ENSG00000081052-COL4A4
Ensembl
ENSG00000081052
,
ENSP00000379866
,
ENST00000396625
PRO
P53420
Pharos - Targets
P53420
GlyGen
P53420
Orphanet
15773
PDB
6WKU
,
5NB1
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