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COL4A4 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-1980248
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
Collagen alpha-4(IV) chain
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type IV (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
P4HB binds Collagen chains (Homo sapiens)
Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
P4HB:Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylase procollagen substrates [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylase procollagen substrates [endoplasmic reticulum lumen] (Homo sapiens)
Collagen propeptides, chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type IV [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen alpha-3(IV), alpha-4(IV), alpha-5(IV) [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen alpha-3(IV), alpha-4(IV) alpha-5(IV) trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Homo sapiens)
P4HB:Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagens and tropocollagens [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type IV [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen alpha-3(IV), alpha-4(IV), alpha-5(IV) [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-4(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
COL4A4 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P53420 COL4A4
Gene Names
COL4A4
Chain
signal peptide:1-38, chain:39-1690
Reference Genes
BioGPS Gene:1286 COL4A4
COSMIC (genes):COL4A4 COL4A4
CTD Gene:1286 COL4A4
dbSNP Gene:1286 COL4A4
ENSEMBL:ENSG00000081052 COL4A4
HGNC:2206 COL4A4
KEGG Gene (Homo sapiens):1286 COL4A4
Monarch:1286 COL4A4
NCBI Gene:1286 COL4A4
OMIM:120131 COL4A4
UCSC:P53420 COL4A4
Reference Transcript
RefSeq:NM_000092.4 COL4A4
RefSeq:XM_005246281.3 COL4A4
Other Identifiers
0001990711
0104850039
11725265_at
11725266_at
1286
16909172
214602_at
229779_at
2602116
2602117
2602118
2602119
2602120
2602121
2602122
2602123
2602125
2602131
2602132
2602134
2602138
2602141
2602142
2602143
2602144
2602145
2602146
2602150
2602151
2602152
2602153
2602154
2602155
2602156
2602157
2602158
2602159
2602160
2602161
2602163
2602164
2602165
2602166
2602169
2602170
2602171
2602172
2602173
2602174
2602175
2602176
2602177
2602178
2602179
2602180
2602181
2602182
2602184
2602185
2602186
2602187
2602188
2602191
2602192
2602193
2602194
2602198
2602199
2602200
2602201
2602202
2602209
2602212
2602216
2602217
2602219
35493_at
5NB1
8059477
88649_at
A0A2R8Y548
A_23_P254522
A_33_P3227400
AAY14670
AAY24061
AB008496
AC073149
AC079235
BAA04214
BAA25065
CAA56943
CAA76763
CCDS42828
COL4A4
COL4A4-201
D17391
D17391_at
ENSG00000081052
ENSP00000379866
ENST00000396625
ENST00000396625.4
EntrezGene:1286
EntrezGene:COL4A4
GE87916
GO:0003674
GO:0005198
GO:0005201
GO:0005575
GO:0005576
GO:0005581
GO:0005587
GO:0005604
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005783
GO:0005788
GO:0007165
GO:0008150
GO:0030020
GO:0030198
GO:0031012
GO:0032836
GO:0032991
GO:0038063
GO:0043226
GO:0048856
GO:0062023
HGNC:2206
Hs.119471.0.A1_3p_at
Hs.180828.0.S2_3p_at
ILMN_1778308
IPR001442
IPR008160
IPR016187
IPR036954
LRG_231
LRG_231t1
MIM:120131
MIM:141200
MIM:203780
NM_000092
NP_000083
PF01391
PF01413
PH_hs_0023458
SM00111
TC02002832.hg
TC02004836.hg
UPI000013D987
X81053
XM_005246281
XM_005246282
XM_006712246
XM_011510557
XM_011510558
XM_011510559
XM_011510560
XM_011510561
XM_011510562
XM_011510565
XM_011510566
XM_011510567
XM_011510568
XM_011510569
XM_011510570
XM_017003296
XM_017003297
XM_017003298
XM_017003299
XM_017003300
XP_005246338
XP_005246339
XP_006712309
XP_011508859
XP_011508860
XP_011508861
XP_011508862
XP_011508863
XP_011508864
XP_011508867
XP_011508868
XP_011508869
XP_011508870
XP_011508871
XP_011508872
XP_016858785
XP_016858786
XP_016858787
XP_016858788
XP_016858789
XR_001738602
XR_001738603
XR_001738604
XR_001738606
XR_001738607
XR_922837
Y17397
Y17398
Y17399
Y17400
Y17401
Y17402
Y17403
Y17404
Y17405
Y17406
Y17407
Y17408
Y17409
Y17410
Y17411
Y17412
Y17413
Y17414
Y17415
Y17416
Y17417
Y17418
Y17419
Y17420
Y17421
Y17422
Y17423
Y17424
Y17425
Y17426
Y17427
Y17428
Y17429
Y17430
Y17431
Y17432
Y17433
Y17434
Y17435
Y17436
Y17437
Y17438
Y17439
Y17440
Y17441
Y17442
Y17443
Participant Of
hasMember
Alpha-4(IV) chains [endoplasmic reticulum lumen]
hasCandidate
Collagen propeptides [endoplasmic reticulum lumen]
Collagen propeptides, chains [endoplasmic reticulum lumen]
Other forms of this molecule
3x4Hyp-GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4 [endoplasmic reticulum lumen]
GalHyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A4 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A4 [endoplasmic reticulum lumen]
5Hyl-COL4A4 [endoplasmic reticulum lumen]
5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
3,4-Hyp 5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
4-Hyp 5-sulfiliminyl collagen alpha-4(IV) chain [extracellular region]
3x4Hyp-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-GalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-5Hyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-COL4A4(39-?) [extracellular region]
GalHyl-COL4A4(39-?) [extracellular region]
GlcGalHyl-COL4A4(?-1690) [extracellular region]
COL4A4(39-?) [extracellular region]
3x4Hyp-GalHyl-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4(?-1690) [extracellular region]
5Hyl-COL4A4(39-?) [extracellular region]
3x4Hyp-GalHyl-COL4A4(?-1690) [extracellular region]
COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4(?-1690) [extracellular region]
5Hyl-COL4A4(?-1690) [extracellular region]
GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-5Hyl-COL4A4(39-?) [extracellular region]
3x4Hyp-COL4A4(?-1690) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4(39-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A4(39-?) [extracellular region]
3x4Hyp-3Hyp-COL4A4(?-1690) [extracellular region]
GalHyl-COL4A4(?-1690) [extracellular region]
COL4A4(39-?) [extracellular region]
3x4Hyp-5Hyl-COL4A4 [extracellular region]
COL4A4 [extracellular region]
GalHyl-COL4A4 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A4 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4 [extracellular region]
3x4Hyp-COL4A4 [extracellular region]
3,4-Hyp Glu-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
4-Hyp 5-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
5-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
3,4-hydroxyprolyl collagen alpha-4(IV) NC1 domain [extracellular region]
Glu-Gal-Hyl-collagen alpha-4(IV) NC1 domain [extracellular region]
5-hydroxylysyl collagen alpha-4(IV) NC1 domain [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A4 NC1 domain [extracellular region]
4-Hyp 5-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
3,4-Hyp 5-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
4-Hyp Glu-Gal-Hyl collagen alpha-4(IV) NC1 domain [extracellular region]
4-hydroxyprolyl collagen alpha-4(IV) NC1 domain [extracellular region]
Collagen alpha-4(IV) NC1 domain [extracellular region]
3x4Hyp-GalHyl-COL4A4 [extracellular region]
3x4Hyp-3Hyp-COL4A4 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A4 [extracellular region]
GlcGalHyl-COL4A4 [extracellular region]
3x4Hyp-GalHyl-COL4A4 [extracellular region]
5Hyl-COL4A4 [extracellular region]
Inferred To
let-2 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Col4a4 [endoplasmic reticulum lumen] (Mus musculus)
Col4a4 [endoplasmic reticulum lumen] (Rattus norvegicus)
COL4A4 [endoplasmic reticulum lumen] (Canis familiaris)
COL4A4 [endoplasmic reticulum lumen] (Dictyostelium discoideum)
COL4A4 [endoplasmic reticulum lumen] (Sus scrofa)
col4a6 [endoplasmic reticulum lumen] (Danio rerio)
Cross References
RefSeq
NP_000083.3
,
XP_005246338.1
OpenTargets
ENSG00000081052
HPA
ENSG00000081052-COL4A4
GeneCards
P53420
Ensembl
ENST00000396625
,
ENSG00000081052
,
ENSP00000379866
PRO
P53420
Orphanet
15773
PDB
5NB1
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