NOTCH1 stimulates HES5 transcription

Stable Identifier
R-HSA-1980078
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NOTCH1 stimulates HES5 transcription
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Binding of the NOTCH1 Coactivator Complex to the HES5 promoter stimulates HES5 transcription (Arnett et al. 2010).
Literature References
PubMed ID Title Journal Year
20972443 Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

McArthur, DG, Kopan, R, Blacklow, SC, Arnett, KL, Hass, M, Aster, JC, Ilagan, MXG

Nat Struct Mol Biol 2010
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NOTCH1 Coactivator Complex:HES5 Gene [nucleoplasm] (Homo sapiens)
Active Unit
NOTCH1 Coactivator Complex [nucleoplasm]
Authored
Orlic-Milacic, M  (2011-11-14)
Egan, SE  (2011-11-14)
Reviewed
Haw, R  (2012-02-06)
Created
Orlic-Milacic, M  (2011-11-09)
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