NOTCH1 stimulates HES5 transcription

Stable Identifier
R-HSA-1980078
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
NOTCH1 stimulates HES5 transcription
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Binding of the NOTCH1 Coactivator Complex to the HES5 promoter stimulates HES5 transcription (Arnett et al. 2010).

Literature References
PubMed ID Title Journal Year
20972443 Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

McArthur, DG, Kopan, R, Blacklow, SC, Arnett, KL, Hass, M, Aster, JC, Ilagan, MXG

Nat Struct Mol Biol 2010
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NOTCH1 Coactivator Complex:HES5 Gene [nucleoplasm] (Homo sapiens)
Active Unit
NOTCH1 Coactivator Complex [nucleoplasm]
Authored
Orlic-Milacic, M  (2011-11-14)
Egan, SE  (2011-11-14)
Reviewed
Haw, R  (2012-02-06)
Created
Orlic-Milacic, M  (2011-11-09)
Cite Us!