JAG2 binds NOTCH2

Stable Identifier
R-HSA-1980061
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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JAG2, expressed on a neighboring cell, binds NOTCH2 and activates intracellular NOTCH2 signaling (Shimizu et al. 2000).

Literature References
PubMed ID Title Journal Year
10958687 Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

Shimizu, K, Chiba, S, Hosoya, N, Kumano, K, Saito, T, Kurokawa, M, Kanda, Y, Hamada, Y, Hirai, H

Mol Cell Biol 2000
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