JAG2 binds NOTCH2

Stable Identifier
R-HSA-1980061
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
JAG2 binds NOTCH2
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
JAG2, expressed on a neighboring cell, binds NOTCH2 and activates intracellular NOTCH2 signaling (Shimizu et al. 2000).
Literature References
PubMed ID Title Journal Year
10958687 Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

Kanda, Y, Kurokawa, M, Shimizu, K, Hirai, H, Kumano, K, Hamada, Y, Saito, T, Chiba, S, Hosoya, N

Mol Cell Biol 2000
Participants
Input
Output
Entity On Other Cell
Participates
as an event of
Inferred From
Jag2 binds Notch2 (Mus musculus)
Authored
Orlic-Milacic, M  (2013-01-11)
Reviewed
Ilagan, MXG  (2013-04-25)
Haw, R  (2013-01-14)
Boyle, S  (2013-04-25)
Created
Orlic-Milacic, M  (2011-11-09)
Cite Us!