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FCGR2B [plasma membrane]
Stable Identifier
R-HSA-197854
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Low affinity immunoglobulin gamma Fc region receptor II-b precursor, FCGB_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
Fc gamma receptors interact with antigen-bound IgG (Homo sapiens)
Antigen-bound antibody bound to lymphoid Fc gamma receptors [plasma membrane] (Homo sapiens)
Lymphoid-expressed Fc-gamma receptors [plasma membrane] (Homo sapiens)
FCGR2B [plasma membrane] (Homo sapiens)
Lymphoid-expressed Fc-gamma receptors [plasma membrane] (Homo sapiens)
FCGR2B [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P31994 FCGR2B
Gene Names
FCGR2B, CD32, FCG2, IGFR2
Chain
signal peptide:1-42, chain:43-310
Reference Genes
BioGPS Gene:2213 FCGR2B
COSMIC (genes):FCGR2B FCGR2B
CTD Gene:2213 FCGR2B
dbSNP Gene:2213 FCGR2B
ENSEMBL:ENSG00000072694 FCGR2B
ENSEMBL_homo_sapiens_GENE:ENSG00000072694.22 FCGR2B
HGNC:3618 FCGR2B
KEGG Gene (Homo sapiens):2213 FCGR2B
Monarch:2213 FCGR2B
NCBI Gene:2213 FCGR2B
OMIM:604590 FCGR2B
UCSC:P31994 FCGR2B
Reference Transcript
RefSeq:XM_017000671.1 FCGR2B
RefSeq:NM_004001.4 FCGR2B
RefSeq:NM_001002274.2 FCGR2B
RefSeq:NM_001002273.2 FCGR2B
RefSeq:XM_017000672.1 FCGR2B
RefSeq:NM_001190828.1 FCGR2B
RefSeq:NM_001002275.2 FCGR2B
Other Identifiers
11726046_s_at
11741517_s_at
11741518_x_at
11741899_s_at
210889_PM_s_at
210889_s_at
211395_PM_x_at
211395_x_at
2213
2363745
2363755
2363821
2363822
2363823
2363829
2363832
2363833
2363836
2363838
2363844
2363846
2363847
2363848
2363849
34663_at
34665_g_at
7906767
7906777
A_23_P34644
A_24_P938284
A_33_P3327617
GE80163
GO:0001540
GO:0001811
GO:0001814
GO:0001818
GO:0002252
GO:0002266
GO:0002313
GO:0002316
GO:0002376
GO:0002436
GO:0002605
GO:0002622
GO:0002638
GO:0002819
GO:0002865
GO:0002922
GO:0002924
GO:0004888
GO:0005515
GO:0005886
GO:0006898
GO:0006909
GO:0006911
GO:0006952
GO:0006954
GO:0007155
GO:0007166
GO:0009617
GO:0009897
GO:0010469
GO:0012501
GO:0016020
GO:0016064
GO:0016192
GO:0019772
GO:0019864
GO:0019886
GO:0021549
GO:0023052
GO:0030154
GO:0030889
GO:0032693
GO:0034330
GO:0038094
GO:0043031
GO:0043197
GO:0043318
GO:0044297
GO:0044877
GO:0045088
GO:0046330
GO:0048856
GO:0050765
GO:0050766
GO:0050776
GO:0050777
GO:0050859
GO:0050869
GO:0060089
GO:0061024
GO:0071219
GO:0090264
GO:0098542
GO:1902564
GO:1902950
GO:1903381
GO:1904646
GO:1905898
GO:2001199
HMNXSV003048056
ILMN_1660027
ILMN_1804174
ILMN_2382403
TC01006338.hg
g182598_3p_a_at
g182598_3p_x_at
Participates
as a member of
Lymphoid-expressed Fc-gamma receptors [plasma membrane] (Homo sapiens)
Inferred To
Fcgr3 [plasma membrane]
(Mus musculus)
Fcgr3 [plasma membrane]
(Rattus norvegicus)
Homologues of FCGR2B [plasma membrane]
(Mus musculus)
Homologues of FCGR2B [plasma membrane]
(Rattus norvegicus)
Homologues of FCGR2B [plasma membrane]
(Sus scrofa)
Fcgr2 [plasma membrane]
(Mus musculus)
Fcgr2 [plasma membrane]
(Rattus norvegicus)
LOC110260307 [plasma membrane]
(Sus scrofa)
FCGR2B [plasma membrane]
(Gallus gallus)
FCGR2B [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001177757.1
,
NP_003992.3
,
NP_001002274.1
,
XP_016856160.1
,
NP_001002273.1
,
NP_001002275.1
,
XP_016856161.1
OpenTargets
ENSG00000072694
GeneCards
P31994
HPA
ENSG00000072694-FCGR2B
Ensembl
ENST00000358671
,
ENST00000236937
,
ENSP00000351497
,
ENST00000367961
,
ENSG00000072694
,
ENSP00000356938
,
ENSP00000236937
PRO
P31994
Pharos - Targets
P31994
Orphanet
21745
PDB
2FCB
,
3WJJ
,
5OCC
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92835 INPP5D
2
p-Y-INPP5D [cytosol]
(R-HSA-9680730)
INPP5D [cytosol]
(R-HSA-197940)
0.702
3
UniProt:P29350 PTPN6
5
PTPN6 [specific granule lumen]
(R-HSA-6799641)
PTPN6 [extracellular region]
(R-HSA-6806315)
PTPN6 [tertiary granule lumen]
(R-HSA-6800952)
PTPN6 [nucleoplasm]
(R-HSA-9008911)
PTPN6 [cytosol]
(R-HSA-197938)
0.669
3
UniProt:P19174 PLCG1
6
p-Y-PLCG1 [cytosol]
(R-HSA-9029082)
p-4Y-PLCG1 [plasma membrane]
(R-HSA-167679)
PLCG1 [cytosol]
(R-HSA-202320)
PLCG1 [plasma membrane]
(R-HSA-167682)
p-Y771,Y783,Y1254-PLCG1 [cytosol]
(R-HSA-202357)
p-Y771,Y783-PLCG1 [plasma membrane]
(R-HSA-1169084)
0.544
2
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