Reactome | F11R [plasma membrane]

F11R [plasma membrane]

Stable Identifier

R-HSA-197845

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

JAM-A, Junctional adhesion molecule 1 precursor, JAM1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9NV29 TM100

Expand all

External Reference Information

External Reference

UniProt:Q9Y624 F11R

Gene Names

F11R, JAM1, JCAM, UNQ264/PRO301

Chain

signal peptide:1-27, chain:28-299

Reference Genes

BioGPS Gene:50848 F11R

COSMIC (genes):F11R F11R

CTD Gene:50848 F11R

dbSNP Gene:50848 F11R

ENSEMBL:ENSG00000158769 F11R

ENSEMBL_homo_sapiens_GENE:ENSG00000158769.19 F11R

HGNC:14685 F11R

KEGG Gene (Homo sapiens):50848 F11R

Monarch:50848 F11R

NCBI Gene:50848 F11R

OMIM:605721 F11R

UCSC:Q9Y624 F11R

Reference Transcript

Other Identifiers

11720460_x_at

11720461_a_at

11720462_at

11720463_x_at

11720464_x_at

11756983_a_at

16695490

221664_PM_s_at

221664_s_at

222354_3p_at

222354_PM_at

222354_at

223000_PM_s_at

223000_s_at

224097_PM_s_at

224097_s_at

2440477

2440478

2440479

2440480

2440481

2440482

2440483

2440484

2440485

2440486

2440488

2440490

2440491

2440492

2440493

2440494

2440495

2440497

2440501

2440502

2440503

50848

56500_at

56502_at

74714_at

78026_at

7921713

A_24_P319364

A_24_P319369

A_33_P3238250

GE62899

GE88609

GO:0001618

GO:0001817

GO:0002376

GO:0005178

GO:0005515

GO:0005576

GO:0005615

GO:0005886

GO:0005911

GO:0005923

GO:0006954

GO:0007010

GO:0007155

GO:0007159

GO:0008360

GO:0016020

GO:0022600

GO:0023052

GO:0030054

GO:0030154

GO:0030165

GO:0030855

GO:0031032

GO:0032956

GO:0032991

GO:0034330

GO:0035025

GO:0035633

GO:0035683

GO:0042060

GO:0042803

GO:0043226

GO:0045296

GO:0046718

GO:0048856

GO:0048870

GO:0050892

GO:0051493

GO:0051497

GO:0070062

GO:0070160

GO:0070161

GO:0071260

GO:0072659

GO:0090557

GO:0090559

GO:0098609

GO:1901731

GO:1902396

GO:1903142

GO:2000810

HMNXSV003003330

Hs.314158.0.A1_3p_s_at

ILMN_2342033

ILMN_2406532

PH_hs_0024996

TC01003412.hg

g11065890_3p_a_at

g13124448_3p_a_at

g5457118_3p_s_at

Participates

as a component of

as an input of

Other forms of this molecule

F11R [cell junction]

Inferred To

F11r [plasma membrane] (Mus musculus)

F11r [plasma membrane] (Rattus norvegicus)

f11r [plasma membrane] (Xenopus tropicalis)

f11r.1 [plasma membrane] (Danio rerio)

F11R [plasma membrane] (Bos taurus)

F11R [plasma membrane] (Canis familiaris)

F11R [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_001335020.1, NP_058642.1

OpenTargets

ENSG00000158769

HPA

ENSG00000158769-F11R

GeneCards

Q9Y624

Ensembl

ENSP00000357005, ENST00000537746, ENSG00000158769, ENSP00000440812, ENST00000368026

PRO

Q9Y624

Pharos - Targets

Q9Y624

PDB

4ODB, 1NBQ, 3EOY, 3TSZ

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43765 SGTA	1	SGTA [cytosol] (R-HSA-5423595)	0.83	11
UniProt:Q9UHJ9-5 PGAP2			0.556	3
UniProt:Q9NV29 TM100			0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:Q5SQN1 SNP47			0.556	3
UniProt:Q96S97 MYADM			0.556	3
UniProt:Q9BV20 MRI1	1	MRI1 [cytosol] (R-HSA-1237095)	0.556	3
UniProt:P78382 SLC35A1	2	SLC35A1 [Golgi membrane] (R-HSA-727812) SLC35A1 V93Cfs*17 [Golgi membrane] (R-HSA-5651957)	0.556	3
UniProt:Q9BRI3 SLC30A2	2	SLC30A2 [endosome membrane] (R-HSA-435363) SLC30A2 [synaptic vesicle membrane] (R-HSA-4084714)	0.556	3
UniProt:P50281 MMP14	3	MMP14(21-582) [Golgi lumen] (R-HSA-1604689) MMP14 [Golgi lumen] (R-HSA-1604724) MMP14 [plasma membrane] (R-HSA-1442472)	0.556	3
UniProt:Q9NP70 AMBN	2	p-AMBN [endoplasmic reticulum lumen] (R-HSA-8956976) AMBN [endoplasmic reticulum lumen] (R-HSA-8956704)	0.556	3
UniProt:Q9BVK8 TM147			0.556	3
UniProt:Q9UI14 PRAF1			0.556	3
UniProt:Q92615 LAR4B			0.556	3
UniProt:P0DN84 DWORF			0.556	3
UniProt:Q8N5M9 JAGN1			0.556	3
UniProt:P49069 CAMLG	1	CAMLG [endoplasmic reticulum membrane] (R-HSA-9609522)	0.556	3
UniProt:Q9P0N8 MARH2			0.556	3
UniProt:Q05513 PRKCZ	5	p-T410,T563-PRKCZ [cytosol] (R-HSA-5218698) PRKCZ [cytosol] (R-HSA-58218) PRKCZ [cell junction] (R-HSA-2134483) p-T410-PRKCZ [cytosol] (R-HSA-437181) pS, p-T410-PRKCZ [cytosol] (R-HSA-9632824)	0.536	2
UniProt:P60033 CD81	1	CD81 [plasma membrane] (R-HSA-197933)	0.527	6
UniProt:Q68D91 MBLC2			0.527	2
UniProt:P29459 IL12A	4	IL12A [Golgi lumen] (R-HSA-8950463) IL12A [endoplasmic reticulum lumen] (R-HSA-8950139) IL12A [late endosome lumen] (R-HSA-8950449) IL12A [extracellular region] (R-HSA-447212)	0.527	2
UniProt:Q9NRD5 PICK1	2	PICK1 [endocytic vesicle membrane] (R-HSA-417017) PICK1 [plasma membrane] (R-HSA-416989)	0.527	2

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