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LAG3 [plasma membrane]
Stable Identifier
R-HSA-197837
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Lymphocyte activation gene-3 protein precursor, LAG3_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
LAG3 (CD233) binds MHC II (Homo sapiens)
LAG3 [plasma membrane] (Homo sapiens)
LAG3:MHC II [plasma membrane] (Homo sapiens)
LAG3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P18627 LAG3
Gene Names
LAG3, FDC
Chain
signal peptide:1-22, chain:23-525, chain:23-
Reference Genes
BioGPS Gene:3902 LAG3
COSMIC (genes):LAG3 LAG3
CTD Gene:3902 LAG3
dbSNP Gene:3902 LAG3
ENSEMBL:ENSG00000089692 LAG3
ENSEMBL_homo_sapiens_GENE:ENSG00000089692.9 LAG3
HGNC:6476 LAG3
KEGG Gene (Homo sapiens):3902 LAG3
Monarch:3902 LAG3
NCBI Gene:3902 LAG3
OMIM:153337 LAG3
UCSC:P18627 LAG3
Reference Transcript
RefSeq:NM_002286.5 LAG3
Other Identifiers
11730060_a_at
11749522_a_at
16747402
206486_PM_at
206486_at
3402758
3402759
3402761
3402762
3402764
3402765
3402766
3402768
3402770
3402771
3402772
3402775
3402777
3402778
36776_at
3902
74689_at
7953418
A_14_P119275
A_23_P116942
GE58280
GO:0002250
GO:0002270
GO:0002376
GO:0003823
GO:0004888
GO:0005515
GO:0005576
GO:0005886
GO:0007155
GO:0007166
GO:0009897
GO:0016020
GO:0023052
GO:0030154
GO:0032703
GO:0042110
GO:0042267
GO:0042289
GO:0045590
GO:0045954
GO:0048856
GO:0050776
GO:0050868
GO:0060089
GO:0098542
HMNXSV003040341
ILMN_1813338
PH_hs_0024797
TC12000091.hg
X51985_at
g11693297_3p_at
Participates
as a component of
LAG3:MHC II [plasma membrane] (Homo sapiens)
as an input of
LAG3 (CD233) binds MHC II (Homo sapiens)
Inferred To
LAG3 [plasma membrane]
(Bos taurus)
LAG3 [plasma membrane]
(Canis familiaris)
LAG3 [plasma membrane]
(Gallus gallus)
LAG3 [plasma membrane]
(Sus scrofa)
Lag3 [plasma membrane]
(Mus musculus)
Lag3 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_002277.4
Guide to Pharmacology - Targets
2932
OpenTargets
ENSG00000089692
GeneCards
P18627
HPA
ENSG00000089692-LAG3
Ensembl
ENSG00000089692
,
ENST00000203629
,
ENST00000441671
,
ENSP00000203629
,
ENSP00000413825
PRO
P18627
Pharos - Targets
P18627
PDB
7TZH
,
7TZG
,
8SO3
,
7UM3
,
8SR0
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08830 FGL1
0.544
3
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