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SIGLEC6 [plasma membrane]
Stable Identifier
R-HSA-197708
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sialic acid binding Ig-like lectin 6 precursor, SIL6_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
Sialic acid binds SIGLEC (Homo sapiens)
SIGLEC [plasma membrane] (Homo sapiens)
SIGLEC6 [plasma membrane] (Homo sapiens)
SIGLEC:sialic acid [plasma membrane] (Homo sapiens)
SIGLEC [plasma membrane] (Homo sapiens)
SIGLEC6 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43699 SIGLEC6
Gene Names
SIGLEC6, CD33L, CD33L1, OBBP1
Chain
signal peptide:1-26, chain:27-453
Reference Genes
BioGPS Gene:946 SIGLEC6
COSMIC (genes):SIGLEC6 SIGLEC6
CTD Gene:946 SIGLEC6
dbSNP Gene:946 SIGLEC6
ENSEMBL:ENSG00000105492 SIGLEC6
ENSEMBL_homo_sapiens_GENE:ENSG00000105492.16 SIGLEC6
HGNC:10875 SIGLEC6
KEGG Gene (Homo sapiens):946 SIGLEC6
Monarch:946 SIGLEC6
NCBI Gene:946 SIGLEC6
OMIM:604405 SIGLEC6
UCSC:O43699 SIGLEC6
Reference Transcript
RefSeq:NM_198845.5 SIGLEC6
RefSeq:NM_001245.6 SIGLEC6
RefSeq:NM_001177547.2 SIGLEC6
RefSeq:NM_001177549.2 SIGLEC6
RefSeq:NM_001177548.2 SIGLEC6
RefSeq:NM_198846.5 SIGLEC6
Other Identifiers
11734205_s_at
11742260_s_at
11762458_x_at
11762489_a_at
16874890
206519_PM_x_at
206519_x_at
206520_PM_x_at
206520_x_at
210796_PM_x_at
210796_x_at
34483_at
3545572
3869100
3869101
3869102
3869103
3869104
3869105
3869106
3869107
3869108
3869109
3869111
3869112
3869114
3869115
3869116
3869117
3869118
3869119
3869120
3869121
3869122
8038861
946
A_23_P4592
A_24_P139028
GE57358
GO:0005515
GO:0005576
GO:0005829
GO:0005886
GO:0007155
GO:0007267
GO:0016020
GO:0023052
GO:0030246
GO:0033691
HMNXSV003017769
ILMN_2299095
PH_hs_0018993
TC19001782.hg
TC19002560.hg
g2913994_3p_at
g2913996_3p_s_at
Participates
as a candidate of
SIGLEC [plasma membrane] (Homo sapiens)
Inferred To
SIGLEC6 [plasma membrane]
(Bos taurus)
SIGLEC6 [plasma membrane]
(Mus musculus)
SIGLEC6 [plasma membrane]
(Sus scrofa)
XB5961956 [plasma membrane]
(Xenopus tropicalis)
LOC110261034 [plasma membrane]
(Sus scrofa)
siglecl2 [plasma membrane]
(Xenopus tropicalis)
LOC119881386 [plasma membrane]
(Canis familiaris)
LOC102152131 [plasma membrane]
(Canis familiaris)
LOC100138951 [plasma membrane]
(Bos taurus)
Siglec5 [plasma membrane]
(Rattus norvegicus)
LOC618268 [plasma membrane]
(Bos taurus)
Cd33 [plasma membrane]
(Rattus norvegicus)
LOC618463 [plasma membrane]
(Bos taurus)
mag [plasma membrane]
(Danio rerio)
Siglech [plasma membrane]
(Mus musculus)
Siglech [plasma membrane]
(Rattus norvegicus)
Homologues of SIGLEC6 [plasma membrane]
(Bos taurus)
Homologues of SIGLEC6 [plasma membrane]
(Canis familiaris)
Homologues of SIGLEC6 [plasma membrane]
(Mus musculus)
Homologues of SIGLEC6 [plasma membrane]
(Rattus norvegicus)
Homologues of SIGLEC6 [plasma membrane]
(Sus scrofa)
Homologues of SIGLEC6 [plasma membrane]
(Xenopus tropicalis)
LOC100515551 [plasma membrane]
(Sus scrofa)
LOC484343 [plasma membrane]
(Canis familiaris)
LOC100686511 [plasma membrane]
(Canis familiaris)
SIGLEC11 [plasma membrane]
(Canis familiaris)
Cross References
RefSeq
NP_001236.4
,
NP_001171019.1
,
NP_001171020.1
,
NP_942142.3
,
NP_001171018.1
,
NP_942143.3
OpenTargets
ENSG00000105492
GeneCards
O43699
HPA
ENSG00000105492-SIGLEC6
Ensembl
ENST00000425629
,
ENSP00000345907
,
ENSG00000105492
,
ENST00000343300
,
ENST00000359982
,
ENSP00000344064
,
ENST00000346477
,
ENSP00000401502
,
ENSP00000353071
,
ENSP00000375674
,
ENST00000436458
,
ENSP00000410679
,
ENST00000391797
PRO
O43699
Pharos - Targets
O43699
HMDB Protein
HMDBP14228
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14192 FHL2
1
FHL2 [nucleoplasm]
(R-HSA-561161)
0.556
3
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