Reactome | SIGLEC10 [plasma membrane]

SIGLEC10 [plasma membrane]

Stable Identifier

R-HSA-197707

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Sialic acid binding Ig-like lectin 10 precursor, SILA_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96LC7 SIGLEC10

Gene Names

SIGLEC10, SLG2, UNQ477/PRO940

Chain

signal peptide:1-16, chain:17-697

Reference Genes

BioGPS Gene:89790 SIGLEC10

COSMIC (genes):SIGLEC10 SIGLEC10

CTD Gene:89790 SIGLEC10

dbSNP Gene:89790 SIGLEC10

ENSEMBL:ENSG00000142512 SIGLEC10

ENSEMBL_homo_sapiens_GENE:ENSG00000142512.15 SIGLEC10

HGNC:15620 SIGLEC10

KEGG Gene (Homo sapiens):89790 SIGLEC10

Monarch:89790 SIGLEC10

NCBI Gene:89790 SIGLEC10

OMIM:606091 SIGLEC10

UCSC:Q96LC7 SIGLEC10

Reference Transcript

Other Identifiers

11738124_x_at

11747873_x_at

11748727_a_at

11752404_x_at

1552806_PM_a_at

1552806_a_at

1552807_PM_a_at

1552807_a_at

16874846

17122174

3839126

3839129

3839131

3839133

3839134

3839135

3868269

3868272

3868273

3868276

3869031

3869032

3869033

3869034

3869035

3869039

3869040

3869041

3869042

3869043

3869044

3869045

3869046

3869047

3869048

3869049

3869050

3869051

3869052

3869053

3869054

3869055

3869056

8038824

89790

A_23_P208182

GE83615

GO:0002250

GO:0002376

GO:0005515

GO:0005576

GO:0005886

GO:0006954

GO:0007155

GO:0016020

GO:0019902

GO:0030246

GO:0033691

GO:0042169

GO:0045087

GO:0098542

GO:0106015

HMNXSV003028088

Hs2.335337.1.S1_3p_a_at

Hs2.335337.1.S2_3p_a_at

ILMN_1655549

PH_hs_0023475

TC19001779.hg

Participates

as a candidate of

SIGLEC [plasma membrane] (Homo sapiens)

Inferred To

Homologues of SIGLEC10 [plasma membrane] (Xenopus tropicalis)

siglec-4 [plasma membrane] (Danio rerio)

XB5961956 [plasma membrane] (Xenopus tropicalis)

siglecl2 [plasma membrane] (Xenopus tropicalis)

LOC100513863 [plasma membrane] (Sus scrofa)

Siglec10 [plasma membrane] (Rattus norvegicus)

LOC484343 [plasma membrane] (Canis familiaris)

SIGLEC10 [plasma membrane] (Bos taurus)

SIGLEC10 [plasma membrane] (Mus musculus)

Cross References

RefSeq

NP_001309034.1, NP_001164630.1, NP_001164632.1, NP_149121.2, NP_001164628.1, NP_001164629.1, NP_001164627.1

Guide to Pharmacology - Targets

3169

OpenTargets

ENSG00000142512

GeneCards

Q96LC7

HPA

ENSG00000142512-SIGLEC10

Ensembl

ENST00000441969, ENSP00000342389, ENSP00000414324, ENST00000442846, ENST00000439889, ENST00000353836, ENSP00000345243, ENSP00000389132, ENSP00000395475, ENSP00000408387, ENST00000436984, ENSG00000142512, ENST00000339313

PRO

Q96LC7

Pharos - Targets

Q96LC7

HMDB Protein

HMDBP14238

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9697006) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) fully glycosylated Spike [virion membrane] (R-COV-9698327) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791)	0.623	2

Cite Us!