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PTPRS [plasma membrane]
Stable Identifier
R-HSA-197680
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Receptor-type protein-tyrosine phosphatase S precursor, PTNS_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
ECM proteoglycans (Homo sapiens)
AGRN binds NCAM1, PTPRS (Homo sapiens)
AGRN:NCAM1, PTPRS [plasma membrane] (Homo sapiens)
NCAM1, PTPRS [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
NCAM1, PTPRS [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Receptor-type tyrosine-protein phosphatases (Homo sapiens)
PRTPRF, PTPRS, PTPRD bind LRRC4B (Homo sapiens)
LRRC4B:PTPRF,PTPRS,PTPRD [plasma membrane] (Homo sapiens)
PTPRF, PTPRS, PTPRD [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
PTPRF, PTPRS, PTPRD [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
PTPRF, PTPRS, PTPRD bind Liprins (Homo sapiens)
LAR,PTPRS,PTPRD:Liprins [plasma membrane] (Homo sapiens)
PTPRF, PTPRS, PTPRD [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
PTPRF, PTPRS, PTPRD [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
PTPRS binds NTRK3 (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
PTPRS:NTRK3 [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
Synaptic adhesion-like molecules (Homo sapiens)
SALM3 binds LAR-RPTP (Homo sapiens)
PTPRF, PTPRS, PTPRD [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
SALM3:LAR-RPTPs [plasma membrane] (Homo sapiens)
PTPRF, PTPRS, PTPRD [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK3 (TRKC) (Homo sapiens)
Protein tyrosine phosphatases dephosphorylate NTRK3 (Homo sapiens)
(PTPRO,PTPRS) [plasma membrane] (Homo sapiens)
PTPRS [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13332 PTPRS
Gene Names
PTPRS
Chain
signal peptide:1-29, chain:30-1948
Reference Genes
BioGPS Gene:5802 PTPRS
COSMIC (genes):PTPRS PTPRS
CTD Gene:5802 PTPRS
dbSNP Gene:5802 PTPRS
ENSEMBL:ENSG00000105426 PTPRS
HGNC:9681 PTPRS
KEGG:hsa:5802 PTPRS
Monarch:5802 PTPRS
NCBI Gene:5802 PTPRS
OMIM:601576 PTPRS
UCSC:Q13332 PTPRS
Reference Transcript
RefSeq:XM_017027067.1 PTPRS
RefSeq:XM_017027066.1 PTPRS
RefSeq:NM_130854.2 PTPRS
RefSeq:NM_130855.2 PTPRS
RefSeq:XM_005259606.2 PTPRS
RefSeq:XM_017027065.1 PTPRS
RefSeq:XM_005259609.1 PTPRS
RefSeq:NM_002850.3 PTPRS
RefSeq:NM_130853.2 PTPRS
Other Identifiers
11719231_a_at
11719232_x_at
11719233_a_at
11737918_a_at
11741609_a_at
11747089_a_at
1246_at
1247_g_at
1555666_PM_at
1555666_at
16867432
210823_PM_s_at
210823_s_at
226571_PM_s_at
226571_s_at
32289_at
3847107
3847111
3847113
3847114
3847116
3847117
3847118
3847119
3847120
3847121
3847122
3847123
3847124
3847125
3847126
3847127
3847128
3847129
3847130
3847133
3847134
3847135
3847136
3847137
3847138
3847139
3847140
3847141
3847142
3847144
3847145
3847146
3847148
3847149
3847150
3847151
3847152
3847153
3847154
3847155
3847157
3847158
3847159
3847160
3847168
3847170
3847173
3847174
3847175
3847176
3847179
3847180
3847181
3847182
3847185
3847186
3847191
3847192
5802
58584_g_at
8032926
A_23_P56163
A_24_P290856
A_33_P3309468
A_33_P3414964
GE62608
GO:0003824
GO:0004721
GO:0004725
GO:0005515
GO:0005829
GO:0005886
GO:0006470
GO:0007155
GO:0008201
GO:0010977
GO:0014069
GO:0016020
GO:0016311
GO:0016787
GO:0021510
GO:0021549
GO:0021766
GO:0021987
GO:0022038
GO:0023052
GO:0030424
GO:0030426
GO:0030517
GO:0030672
GO:0031410
GO:0032687
GO:0032688
GO:0034164
GO:0034330
GO:0035335
GO:0035374
GO:0042734
GO:0043005
GO:0043204
GO:0043226
GO:0043395
GO:0045202
GO:0048671
GO:0048681
GO:0048856
GO:0050804
GO:0050808
GO:0061000
GO:0070062
GO:0090557
GO:0098685
GO:0098839
GO:0098978
GO:0099151
GO:0099537
GO:0099560
GO:0140096
HMNXSV003022236
HMNXSV003050945
Hs.294141.0.A1_3p_at
Hs2.159534.4.S1_3p_at
ILMN_1656338
ILMN_2365644
PH_hs_0040767
TC19001076.hg
TC19002299.hg
TC19002300.hg
U35234_at
U40317_s_at
g1407624_3p_a_at
Participates
as a member of
NCAM1, PTPRS [plasma membrane] (Homo sapiens)
PTPRF, PTPRS, PTPRD [plasma membrane] (Homo sapiens)
as a component of
PTPRS:NTRK3 [plasma membrane] (Homo sapiens)
as an input of
PTPRS binds NTRK3 (Homo sapiens)
as a candidate of
(PTPRO,PTPRS) [plasma membrane] (Homo sapiens)
Inferred To
PTP3 [plasma membrane]
(Saccharomyces cerevisiae)
pyp2 [plasma membrane]
(Schizosaccharomyces pombe)
PTP1 [plasma membrane]
(Saccharomyces cerevisiae)
PTPRS [plasma membrane]
(Bos taurus)
PTPRS [plasma membrane]
(Caenorhabditis elegans)
PTPRS [plasma membrane]
(Gallus gallus)
PTPRS [plasma membrane]
(Mus musculus)
PTPRS [plasma membrane]
(Rattus norvegicus)
PTPRS [plasma membrane]
(Sus scrofa)
ptpA1-2 [plasma membrane]
(Dictyostelium discoideum)
pyp1 [plasma membrane]
(Schizosaccharomyces pombe)
ptpB [plasma membrane]
(Dictyostelium discoideum)
pyp3 [plasma membrane]
(Schizosaccharomyces pombe)
Homologues of PTPRS [plasma membrane]
(Dictyostelium discoideum)
Homologues of PTPRS [plasma membrane]
(Saccharomyces cerevisiae)
Homologues of PTPRS [plasma membrane]
(Schizosaccharomyces pombe)
ptpC [plasma membrane]
(Dictyostelium discoideum)
PTP2 [plasma membrane]
(Saccharomyces cerevisiae)
Cross References
RefSeq
XP_005259663.1
,
NP_570923.2
,
NP_570924.2
,
NP_570925.2
,
XP_005259666.1
,
XP_016882554.1
,
NP_002841.3
,
XP_016882556.1
,
XP_016882555.1
Guide to Pharmacology - Targets
1866
OpenTargets
ENSG00000105426
ENSEMBL
ENSG00000105426
,
ENSP00000262963
,
ENSP00000465443
,
ENSP00000467537
,
ENST00000592099
,
ENST00000587303
,
ENSP00000467398
,
ENST00000588012
,
ENST00000262963
ZINC - Substances
PTPRS_HUMAN
ZINC target
Q13332
PRO
Q13332
GlyGen
Q13332
PDB
4BPC
,
2FH7
,
4PBX
,
2YD2
,
2YD3
,
2YD9
HPA
ENSG00000105426-PTPRS
GeneCards
PTPRS
Pharos - Targets
Q13332
ZINC - Predictions - Purchasable
PTPRS_HUMAN
HMDB Protein
HMDBP08950
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q16288 NTRK3
6
p-5Y-NTRK3 [plasma membrane]
(R-HSA-9034718)
NTRK3 [plasma membrane]
(R-HSA-6798240)
NTRK3(496-641) [cytosol]
(R-HSA-9603542)
NTRK3(496-641) [mitochondrial outer membrane]
(R-HSA-9603557)
NTRK3(642-839) [cytosol]
(R-HSA-9603540)
NTRK3(32-495) [plasma membrane]
(R-HSA-9603541)
0.527
2
UniProt:Q16849 PTPRN
0.508
5
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