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SIRPG [plasma membrane]
Stable Identifier
R-HSA-197571
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
SIRP gamma, Signal-regulatory protein gamma
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Signal regulatory protein family interactions (Homo sapiens)
SIRP gamma binds CD47 (Homo sapiens)
SIRP gamma:CD47 [plasma membrane] (Homo sapiens)
SIRPG [plasma membrane] (Homo sapiens)
SIRPG [plasma membrane] (Homo sapiens)
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
CD47 binds SIRP (Homo sapiens)
CD47-binding SIRPs [plasma membrane] (Homo sapiens)
SIRPG [plasma membrane] (Homo sapiens)
CD47-binding SIRPs:CD47 [plasma membrane] (Homo sapiens)
CD47-binding SIRPs [plasma membrane] (Homo sapiens)
SIRPG [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9P1W8 SIRPG
Gene Names
SIRPG, SIRPB2
Chain
signal peptide:1-28, chain:29-387
Reference Genes
BioGPS Gene:55423 SIRPG
COSMIC (genes):SIRPG SIRPG
CTD Gene:55423 SIRPG
dbSNP Gene:55423 SIRPG
ENSEMBL:ENSG00000089012 SIRPG
ENSEMBL_homo_sapiens_GENE:ENSG00000089012.14 SIRPG
HGNC:15757 SIRPG
KEGG Gene (Homo sapiens):55423 SIRPG
Monarch:55423 SIRPG
NCBI Gene:55423 SIRPG
OMIM:605466 SIRPG
UCSC:Q9P1W8 SIRPG
Reference Transcript
RefSeq:NM_080816.2 SIRPG
RefSeq:NM_001039508.1 SIRPG
RefSeq:XM_011529286.2 SIRPG
RefSeq:NM_018556.3 SIRPG
Other Identifiers
11740296_a_at
11754881_a_at
16916515
220485_PM_s_at
220485_s_at
234742_PM_at
234742_at
3873659
3894736
3894750
3894766
3894767
3894768
3894773
3894777
3894778
3894779
3894781
3894782
3894783
3894784
3894786
3894788
3894789
47039_at
55423
8064485
A_23_P28857
A_24_P353208
A_33_P3343872
GE62569
GO:0002376
GO:0005515
GO:0005886
GO:0007155
GO:0007267
GO:0008284
GO:0008285
GO:0016020
GO:0016192
GO:0022409
GO:0023052
GO:0035556
GO:0050766
GO:0050870
GO:0051716
HMNXSV003014491
Hs.50716.1.S1_3p_a_at
ILMN_1676780
ILMN_1771801
ILMN_2383058
PH_hs_0028900
TC20000555.hg
Participates
as a component of
SIRP gamma:CD47 [plasma membrane] (Homo sapiens)
as an input of
SIRP gamma binds CD47 (Homo sapiens)
as a member of
CD47-binding SIRPs [plasma membrane] (Homo sapiens)
Inferred To
Sirpd [plasma membrane]
(Mus musculus)
Gm5150 [plasma membrane]
(Mus musculus)
SIRPG [plasma membrane]
(Canis familiaris)
SIRPG [plasma membrane]
(Gallus gallus)
SIRPG [plasma membrane]
(Sus scrofa)
SIRPB1 [plasma membrane]
(Bos taurus)
Homologues of SIRPG [plasma membrane]
(Bos taurus)
Homologues of SIRPG [plasma membrane]
(Canis familiaris)
Homologues of SIRPG [plasma membrane]
(Gallus gallus)
Homologues of SIRPG [plasma membrane]
(Mus musculus)
Homologues of SIRPG [plasma membrane]
(Rattus norvegicus)
Homologues of SIRPG [plasma membrane]
(Sus scrofa)
LOC100736623 [plasma membrane]
(Sus scrofa)
LOC104973826 [plasma membrane]
(Bos taurus)
LOC536097 [plasma membrane]
(Bos taurus)
SIRPA [plasma membrane]
(Bos taurus)
SIRPA [plasma membrane]
(Canis familiaris)
SIRPA [plasma membrane]
(Sus scrofa)
LOC119868972 [plasma membrane]
(Canis familiaris)
Sirpb1a [plasma membrane]
(Mus musculus)
AABR07008876.1 [plasma membrane]
(Rattus norvegicus)
Sirpb2 [plasma membrane]
(Rattus norvegicus)
Sirpal1 [plasma membrane]
(Rattus norvegicus)
Sirpb1b [plasma membrane]
(Mus musculus)
LOC100739707 [plasma membrane]
(Sus scrofa)
LOC100909964 [plasma membrane]
(Rattus norvegicus)
Sirpb1c [plasma membrane]
(Mus musculus)
LOC102161654 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001034597.1
,
NP_543006.2
,
XP_011527588.1
,
NP_061026.2
OpenTargets
ENSG00000089012
GeneCards
Q9P1W8
HPA
ENSG00000089012-SIRPG
Ensembl
ENSP00000370992
,
ENSG00000089012
,
ENST00000381583
,
ENST00000381580
,
ENST00000303415
,
ENSP00000305529
,
ENST00000344103
,
ENST00000216927
,
ENSP00000216927
,
ENSP00000342759
,
ENSP00000370995
PRO
Q9P1W8
Pharos - Targets
Q9P1W8
PDB
2JJW
,
4I2X
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50440 GATM
1
GATM [mitochondrial intermembrane space]
(R-HSA-71267)
0.556
3
UniProt:P01100 FOS
2
FOS [nucleoplasm]
(R-HSA-450216)
p-T325,T331,S362,S374-FOS [nucleoplasm]
(R-HSA-450283)
0.556
3
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