Reactome | POLR3C [cytosol]

POLR3C [cytosol]

Stable Identifier

R-HSA-1964448

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

HsRPC3, RPC3, RPC62, DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase III subunit C, RNA polymerase III 62 kDa subunit

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BUI4 POLR3C

Gene Names

POLR3C

Chain

chain:1-534

Reference Genes

BioGPS Gene:10623 POLR3C

COSMIC (genes):POLR3C POLR3C

CTD Gene:10623 POLR3C

dbSNP Gene:10623 POLR3C

ENSEMBL:ENSG00000186141 POLR3C

HGNC:30076 POLR3C

KEGG:hsa:10623 POLR3C

Monarch:10623 POLR3C

NCBI Gene:10623 POLR3C

OMIM:617454 POLR3C

UCSC:Q9BUI4 POLR3C

Reference Transcript

Other Identifiers

10623

11721549_a_at

11721550_x_at

11745254_a_at

16692122

16692135

209382_PM_at

209382_at

210573_PM_s_at

210573_s_at

2356588

2356591

2432652

2432653

2432654

2432655

2432656

2432657

2432658

2432659

2432660

2432661

2432662

2432663

2432664

2432665

2432666

2432667

2432668

2432669

2432670

2432671

2432672

2432673

2432674

2432675

2432676

2432677

2432678

2432679

2432680

2432681

2432682

2432683

2432684

2432685

2432686

2432687

2432688

2432689

2432690

2432691

2432692

2432693

2432694

2432695

2432696

34671_at

71470_at

782_at

7919217

7919226

A_23_P35256

A_24_P920271

A_33_P3273444

GE541510

GE61592

GO:0000428

GO:0002376

GO:0003677

GO:0003697

GO:0003824

GO:0003899

GO:0005515

GO:0005634

GO:0005654

GO:0005666

GO:0005829

GO:0006351

GO:0006355

GO:0006359

GO:0016740

GO:0032728

GO:0043226

GO:0045087

GO:0045089

GO:0051607

GO:0098542

GO:0140098

HMNXSV003015968

HMNXSV003021803

ILMN_1795678

PH_hs_0028030

PH_hs_0032324

TC01003111.hg

TC01003112.hg

U93867_at

g13325209_3p_a_at

g2228747_3p_at

Participates

as a component of

HsRPC6:HsRPC3:HsRPC7 [cytosol] (Homo sapiens)

Other forms of this molecule

POLR3C [nucleoplasm]

Cross References

OpenTargets

ENSG00000186141

ENSEMBL

ENSP00000334564, ENSG00000186141, ENST00000698751, ENSP00000513913, ENST00000334163

HPA

ENSG00000186141-POLR3C

GeneCards

POLR3C

PRO

Q9BUI4

Pharos - Targets

Q9BUI4

GlyGen

Q9BUI4

HMDB Protein

HMDBP11924

PDB

7FJJ, 7FJI, 7AE1, 8ITY, 5AFQ, 7A6H, 7DN3, 2XV4, 7DU2, 7D58, 7AE3, 8IUH, 7AEA, 7D59, 2XUB, 7AST, 8IUE

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.775	6
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.718	6
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.666	4
UniProt:P61218 POLR2F	2	POLR2F [cytosol] (R-HSA-1964441) POLR2F [nucleoplasm] (R-HSA-83714)	0.643	5
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q13464 ROCK1	6	ROCK1 [cytosol] (R-HSA-212509) ROCK1(1-1113) [cytosol] (R-HSA-212523) ROCK1(1114-1354) [cytosol] (R-HSA-212524) Activated ROCK1 [cytosol] (R-HSA-4687777) ROCK1 [secretory granule lumen] (R-HSA-6804967) ROCK1 [extracellular region] (R-HSA-6806527)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.527	4
UniProt:P52292 KPNA2	2	KPNA2 [cytosol] (R-HSA-205976) KPNA2 [nucleoplasm] (R-HSA-206045)	0.527	2