AKR1B1 [cytosol]

Stable Identifier
R-HSA-196063
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Aldehyde reductase
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
8281941 Sequence of pig lens aldose reductase and electrospray mass spectrometry of non-covalent and covalent complexes

Van Dorsselaer, A, Andriantomanga, V, Barth, P, Biellmann, JF, Kieffer, S, Reymann, JM, Potier, N, Klarskov, K, Jaquinod, M, Sorokine, O

Eur. J. Biochem. 1993
External Reference Information
External Reference
UniProt:P15121 AKR1B1
Gene Names
AKR1B1, ALDR1, ALR2
Chain
initiator methionine:, chain:2-316
Reference Genes
BioGPS Gene:231 AKR1B1
COSMIC (genes):AKR1B1 AKR1B1
CTD Gene:231 AKR1B1
dbSNP Gene:231 AKR1B1
ENSEMBL:ENSG00000085662 AKR1B1
ENSEMBL_homo_sapiens_GENE:ENSG00000085662.14 AKR1B1
HGNC:381 AKR1B1
KEGG Gene (Homo sapiens):231 AKR1B1
Monarch:231 AKR1B1
NCBI Gene:231 AKR1B1
OMIM:103880 AKR1B1
UCSC:P15121 AKR1B1
Reference Transcript
Other Identifiers
11715430_a_at
201272_PM_at
201272_at
231
2382513
2629990
3073998
3073999
3074000
3074001
3074005
3074007
3074010
3074011
3074013
3074015
3074017
3074020
3074027
3074028
3364484
36589_at
3859008
3859013
8143054
A_23_P258190
GE57522
GE59725
GO:0001523
GO:0001758
GO:0002070
GO:0003014
GO:0003091
GO:0003824
GO:0004032
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005975
GO:0006091
GO:0006629
GO:0006693
GO:0006700
GO:0006766
GO:0009055
GO:0012501
GO:0016491
GO:0019853
GO:0022900
GO:0030154
GO:0035809
GO:0036130
GO:0042572
GO:0043066
GO:0043226
GO:0043795
GO:0044597
GO:0044598
GO:0046370
GO:0047655
GO:0047939
GO:0047956
GO:0048856
GO:0052650
GO:0070062
GO:0071475
GO:0072205
GO:1901135
HMNXSV003052930
ILMN_1701731
PH_hs_0035452
X15414_at
g4502048_3p_at
Inferred To
Homologues of AKR1B1 [cytosol] (Drosophila melanogaster)
ARY [cytosol] (Drosophila melanogaster)
AKR1B1 [cytosol] (Bos taurus)
AKR1B1 [cytosol] (Caenorhabditis elegans)
AKR1B1 [cytosol] (Canis familiaris)
AKR1B1 [cytosol] (Danio rerio)
AKR1B1 [cytosol] (Dictyostelium discoideum)
AKR1B1 [cytosol] (Drosophila melanogaster)
AKR1B1 [cytosol] (Gallus gallus)
AKR1B1 [cytosol] (Mus musculus)
AKR1B1 [cytosol] (Rattus norvegicus)
AKR1B1 [cytosol] (Saccharomyces cerevisiae)
AKR1B1 [cytosol] (Schizosaccharomyces pombe)
AKR1B1 [cytosol] (Sus scrofa)
AKR1B1 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
3MC5, 2NVC, 2IKI, 8FH7, 2NVD, 2FZ8, 6F7R, 2IKJ, 1Z8A, 3RX3, 1T41, 2DV0, 1X98, 3DN5, 4QX4, 3LZ5, 2DUZ, 3BCJ, 6Y1P, 4LBR, 1X96, 8AE9, 8B3N, 2ACQ, 5OU0, 3GHR, 2J8T, 6TUF, 3GHS, 3Q67, 8B3R, 2FZ9, 2PDX, 3S3G, 3LQG, 2PDJ, 2PFH, 2FZB, 8BJL, 2PDY, 2PF8, 1ADS, 4PR4, 2PDU, 1PWM, 2HVO, 8AUU, 2HVN, 8B34, 6F81, 2PDI, 4YU1, 3RX4, 5OUJ, 1XGD, 2AGT, 8FH9, 6T3P, 6T27, 2DUX, 2PDC, 4Q7B, 2IPW, 6F8O, 2PDF, 3ONB, 2IQ0, 4LBS, 1Z89, 1X97, 3LD5, 8AQG, 2PZN, 1AZ2, 4IGS, 3U2C, 2PD5, 2PDH, 8FH6, 4GCA, 4LB4, 2PDW, 4YS1, 6T7Q, 5OUK, 2IS7, 1T40, 6TD8, 4NKC, 2PDP, 3M4H, 4LB3, 3LBO, 2ACU, 3P2V, 1IEI, 2I17, 2PDQ, 5HA7, 2F2K, 1US0, 6T5G, 2I16, 2PDM, 3MB9, 2FZD, 3LQL, 2HV5, 2R24, 8A4N, 4JIR, 4PUW, 4PUU, 2PDN, 6TUC, 2PDB, 1MAR, 2IQD, 2PD9, 8FH5, 2ISF, 4QXI, 6SYW, 6F82, 2IKH, 2PDG, 2INZ, 3G5E, 8CNP, 1AZ1, 8FH8, 2ACS, 3ONC, 1EL3, 6XUM, 1EF3, 3RX2, 4LAZ, 3M0I, 4PRT, 1ABN, 4QR6, 3LZ3, 2PEV, 1PWL, 3GHU, 3V36, 4LAU, 6Y03, 3T42, 4PRR, 2IKG, 2QXW, 4GQ0, 3LEP, 3M64, 4RPQ, 3GHT, 3V35, 4QBX, 4XZI, 2INE, 3LEN, 2ACR, 4XZH, 8B66, 8CNF, 2PDL, 6TXP, 8AQP, 3Q65, 6F84, 1Z3N, 2PDK
ZINC - Investigational
ZINC - Metabolites
IntEnz
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (3)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9BUY7 EFC11      0.556 3
 UniProt:P0DTD8 NS7B      0.547 2
 UniProt:P55345 ANM2      0.463 2
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