NRP-2 associates with VEGFR1 forming complexes on cell surface

Stable Identifier
R-HSA-195418
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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NRP-2 associates with VEGFR-1 on the plasma membrane. As NRP-2 lacks an intracellular domain, this association may be the means by which NRP-2 participates in VEGF-induced signaling. This interaction requires VEGF to bridge between NRP and the receptor.

Literature References
PubMed ID Title Journal Year
11278319 Vascular endothelial growth factor receptor-1 and neuropilin-2 form complexes

Gluzman-Poltorak, Z, Cohen, T, Shibuya, M, Neufeld, G

J Biol Chem 2001
Participants
Participant Of
Orthologous Events
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Created