Reactome | ARHGAP1 [cytosol]

ARHGAP1 [cytosol]

Stable Identifier

R-HSA-195193

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

RhoGAP1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q07960 ARHGAP1

Gene Names

ARHGAP1, CDC42GAP, RHOGAP1

Chain

chain:1-439

Reference Genes

BioGPS Gene:392 ARHGAP1

COSMIC (genes):ARHGAP1 ARHGAP1

CTD Gene:392 ARHGAP1

dbSNP Gene:392 ARHGAP1

ENSEMBL:ENSG00000175220 ARHGAP1

ENSEMBL_homo_sapiens_GENE:ENSG00000175220.12 ARHGAP1

HGNC:673 ARHGAP1

KEGG Gene (Homo sapiens):392 ARHGAP1

Monarch:392 ARHGAP1

NCBI Gene:392 ARHGAP1

OMIM:602732 ARHGAP1

UCSC:Q07960 ARHGAP1

Reference Transcript

Other Identifiers

11716238_at

11747362_x_at

16737759

202117_PM_at

202117_at

216689_PM_x_at

216689_x_at

31451_at

3371674

3371675

3371676

3371677

3371679

3371680

3371681

3371682

3371683

3371685

3371690

3371695

3371696

3371697

3371706

392

39700_at

552_at

553_g_at

7947681

A_23_P314070

A_23_P44057

GE80038

GO:0005096

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005768

GO:0005829

GO:0007165

GO:0007264

GO:0007266

GO:0010008

GO:0016192

GO:0016197

GO:0017124

GO:0023052

GO:0031267

GO:0031410

GO:0033572

GO:0043226

GO:0045296

GO:0048471

GO:0051056

GO:0070062

GO:0097443

GO:0098772

GO:2001136

HMNXSV003049551

Hs.138860.0.S2_3p_at

Hs.138860.1.S1_3p_a_at

ILMN_1732060

PH_hs_0008335

PH_hs_0012420

TC11001723.hg

U02570_at

Participates

as a candidate of

as a member of

Inferred To

ECM25 [cytosol] (Saccharomyces cerevisiae)

ARHGAP1 [cytosol] (Bos taurus)

ARHGAP1 [cytosol] (Canis familiaris)

ARHGAP1 [cytosol] (Dictyostelium discoideum)

ARHGAP1 [cytosol] (Gallus gallus)

ARHGAP1 [cytosol] (Sus scrofa)

rga6 [cytosol] (Schizosaccharomyces pombe)

arhgap1 [cytosol] (Danio rerio)

arhgap1 [cytosol] (Xenopus tropicalis)

rga-1 [cytosol] (Caenorhabditis elegans)

RhoGAP68F [cytosol] (Drosophila melanogaster)

Arhgap1 [cytosol] (Mus musculus)

Arhgap1 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

XP_011518397.1, NP_004299.1

OpenTargets

ENSG00000175220

HPA

ENSG00000175220-ARHGAP1

GeneCards

Q07960

Ensembl

ENST00000311956, ENSP00000310491, ENSG00000175220

PRO

Q07960

Pharos - Targets

Q07960

PDB

1TX4, 1OW3, 5M70, 1RGP, 1AM4, 7QSC, 1GRN, 5M6X, 2NGR, 7QTM, 6R3V

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61586 RHOA	6	RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082) RHOA [cytosol] (R-HSA-194866) RHOA [cell junction] (R-HSA-2134503) RHOA [plasma membrane] (R-HSA-194510)	0.692	3
UniProt:P02675 FGB	5	FGB(31-491) [platelet alpha granule lumen] (R-HSA-140921) FGB(31-491) [extracellular region] (R-HSA-140846) FGB [plasma membrane] (R-HSA-140917) FGB(31-44) [extracellular region] (R-HSA-140876) FGB [extracellular region] (R-HSA-140584)	0.527	2

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