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RASGRF2 [cytosol]
Stable Identifier
R-HSA-194944
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
RasGRF2
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
RASGRF2 [cytosol] (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
RASGRF2 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
RASGRF2 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
RASGRF2 [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
RASGRF2 [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
RASGRF2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14827 RASGRF2
Gene Names
RASGRF2, GRF2
Chain
chain:1-1237
Reference Genes
BioGPS Gene:5924 RASGRF2
COSMIC (genes):RASGRF2 RASGRF2
CTD Gene:5924 RASGRF2
dbSNP Gene:5924 RASGRF2
ENSEMBL:ENSG00000113319 RASGRF2
ENSEMBL_homo_sapiens_GENE:ENSG00000113319.13 RASGRF2
HGNC:9876 RASGRF2
KEGG Gene (Homo sapiens):5924 RASGRF2
Monarch:5924 RASGRF2
NCBI Gene:5924 RASGRF2
OMIM:606614 RASGRF2
UCSC:O14827 RASGRF2
Reference Transcript
RefSeq:NM_006909.2 RASGRF2
Other Identifiers
11736820_a_at
16986777
228109_PM_at
228109_at
2817944
2817956
2817961
2817962
2817968
2817969
2817970
2817973
2817974
2817976
2817982
2817984
2817985
2817986
2817991
2817992
2817993
2817994
2817995
2817996
2817998
2818000
2818011
2818017
2818018
2818019
2818021
2818023
2818028
2818029
2818030
2818031
2818032
2818034
2818036
2818037
59086_at
5924
60508_at
8106660
A_14_P200941
A_23_P133386
GE85782
GO:0005085
GO:0005515
GO:0005516
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0005886
GO:0007264
GO:0007265
GO:0016020
GO:0023052
GO:0034976
GO:0043226
GO:0051056
GO:0060291
GO:0098772
HMNXSV003037903
Hs.187497.0.A1_3p_at
ILMN_1753377
PH_hs_0024854
TC05000401.hg
TC05002478.hg
Participates
as a member of
RHOA GEFs [cytosol] (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
as a candidate of
CDC42 GEFs [cytosol] (Homo sapiens)
Other forms of this molecule
RASGRF2 [plasma membrane]
Inferred To
gefR [cytosol]
(Dictyostelium discoideum)
gefA [cytosol]
(Dictyostelium discoideum)
gefI [cytosol]
(Dictyostelium discoideum)
gefS [cytosol]
(Dictyostelium discoideum)
gefB [cytosol]
(Dictyostelium discoideum)
Rasgrf2 [cytosol]
(Mus musculus)
Rasgrf2 [cytosol]
(Rattus norvegicus)
gefJ [cytosol]
(Dictyostelium discoideum)
gefY [cytosol]
(Dictyostelium discoideum)
gefH [cytosol]
(Dictyostelium discoideum)
RASGRF2 [cytosol]
(Bos taurus)
RASGRF2 [cytosol]
(Canis familiaris)
RASGRF2 [cytosol]
(Dictyostelium discoideum)
RASGRF2 [cytosol]
(Gallus gallus)
RASGRF2 [cytosol]
(Sus scrofa)
gefN [cytosol]
(Dictyostelium discoideum)
gefE [cytosol]
(Dictyostelium discoideum)
gefV [cytosol]
(Dictyostelium discoideum)
gefAA [cytosol]
(Dictyostelium discoideum)
gefD [cytosol]
(Dictyostelium discoideum)
gefM [cytosol]
(Dictyostelium discoideum)
gefG [cytosol]
(Dictyostelium discoideum)
Homologues of RASGRF2 [cytosol]
(Dictyostelium discoideum)
rasgrf2 [cytosol]
(Danio rerio)
rasgrf2 [cytosol]
(Xenopus tropicalis)
gefL [cytosol]
(Dictyostelium discoideum)
gefQ [cytosol]
(Dictyostelium discoideum)
gefF [cytosol]
(Dictyostelium discoideum)
gefK [cytosol]
(Dictyostelium discoideum)
gflD [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_008840.1
OpenTargets
ENSG00000113319
GeneCards
O14827
HPA
ENSG00000113319-RASGRF2
Ensembl
ENST00000265080
,
ENSP00000265080
,
ENSG00000113319
PRO
O14827
Pharos - Targets
O14827
HMDB Protein
HMDBP07970
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