Reactome | RHOG [cytosol]

RHOG [cytosol]

Stable Identifier

R-HSA-194909

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

RhoG,

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Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RHOG GTPase cycle (Homo sapiens)
        
        GDIs block activation of RHOG (Homo sapiens)
        
        RHOG GDIs:RHOG:GDP [cytosol] (Homo sapiens)
        
        RHOG:GDP [cytosol] (Homo sapiens)
        
        RHOG [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P84095 RHOG

Gene Names

RHOG, ARHG

Chain

chain:1-188, propeptide:189-191

Reference Genes

BioGPS Gene:391 RHOG

COSMIC (genes):RHOG RHOG

CTD Gene:391 RHOG

dbSNP Gene:391 RHOG

ENSEMBL:ENSG00000177105 RHOG

HGNC:672 RHOG

KEGG:hsa:391 RHOG

Monarch:391 RHOG

NCBI Gene:391 RHOG

OMIM:179505 RHOG

UCSC:P84095 RHOG

Reference Transcript

Other Identifiers

11717636_s_at

11717637_x_at

16734744

203175_PM_at

203175_at

3360007

3360008

3360009

3360010

3360011

3360012

3360014

3360015

3360016

36902_at

391

7945944

A_23_P150718

A_33_P3317376

GE59868

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005789

GO:0005829

GO:0005856

GO:0005886

GO:0005925

GO:0006355

GO:0007010

GO:0007015

GO:0007163

GO:0007264

GO:0007266

GO:0008045

GO:0008284

GO:0008360

GO:0016601

GO:0016787

GO:0019901

GO:0030036

GO:0030667

GO:0030865

GO:0031410

GO:0032956

GO:0042995

GO:0043226

GO:0043652

GO:0045893

GO:0048870

GO:0060326

GO:0061024

GO:0070062

GO:0090630

GO:0098794

GO:0098978

GO:0150052

GO:1900027

GO:1903078

HMNXSV003051689

ILMN_1739792

PH_hs_0004272

TC11001304.hg

X61587_at

g4502218_3p_at

Participates

as a component of

RHOG:GDP [cytosol] (Homo sapiens)

as a member of

Other forms of this molecule

RHOG [secretory granule membrane]

RHOG [endoplasmic reticulum membrane]

RHOG [plasma membrane]

Inferred To

rhog [cytosol] (Xenopus tropicalis)

racQ [cytosol] (Dictyostelium discoideum)

Homologues of RHOG [cytosol] (Caenorhabditis elegans)

Homologues of RHOG [cytosol] (Dictyostelium discoideum)

Homologues of RHOG [cytosol] (Drosophila melanogaster)

racP [cytosol] (Dictyostelium discoideum)

RHOG [cytosol] (Bos taurus)

RHOG [cytosol] (Caenorhabditis elegans)

RHOG [cytosol] (Canis familiaris)

RHOG [cytosol] (Dictyostelium discoideum)

RHOG [cytosol] (Drosophila melanogaster)

RHOG [cytosol] (Gallus gallus)

RHOG [cytosol] (Mus musculus)

RHOG [cytosol] (Sus scrofa)

Rac-1 [cytosol] (Caenorhabditis elegans)

Rhog [cytosol] (Rattus norvegicus)

rhogb [cytosol] (Danio rerio)

Cross References

RefSeq

XP_016873208.1, XP_005252973.1, NP_001656.2

ENSEMBL

ENSP00000436932, ENSP00000339467, ENST00000533217, ENSP00000380175, ENSP00000380176, ENSG00000177105, ENST00000396978, ENST00000396979, ENST00000351018

OpenTargets

ENSG00000177105

GeneCards

RHOG

HPA

ENSG00000177105-RHOG

PRO

P84095

Pharos - Targets

P84095

PDB

8ZJ2, 7Y4A, 8XM7, 6UKA

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92556 ELMO1	1	ELMO1 [cytosol] (R-HSA-200932)	0.623	4
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate [ChEBI:16152]	3	PI(3,4)P2 [early endosome membrane] (R-ALL-1806238) PI(3,4)P2 [Golgi membrane] (R-ALL-1806230) PI(3,4)P2 [plasma membrane] (R-ALL-202247)	0.544	2
1-phosphatidyl-1D-myo-inositol 4-phosphate [ChEBI:17526]	5	PI4P [clathrin-coated endocytic vesicle membrane] (R-ALL-8868704) PI4P [early endosome membrane] (R-ALL-1806180) PI4P [endoplasmic reticulum membrane] (R-ALL-1806234) PI4P [Golgi membrane] (R-ALL-1806217) PI4P [plasma membrane] (R-ALL-392417)	0.544	2
UniProt:P52565 ARHGDIA	1	ARHGDIA [cytosol] (R-HSA-194478)	0.527	2