Reactome | MSMO1 [endoplasmic reticulum membrane]

MSMO1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-194648

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

SC4MOL, C-4 methylsterol oxidase

Locations in the PathwayBrowser for interactor UniProt:Q16581 C3AR1

Expand all

External Reference Information

External Reference

UniProt:Q15800 MSMO1

Gene Names

MSMO1, DESP4, ERG25, SC4MOL

Chain

chain:1-293

Reference Genes

BioGPS Gene:6307 MSMO1

COSMIC (genes):MSMO1 MSMO1

CTD Gene:6307 MSMO1

dbSNP Gene:6307 MSMO1

ENSEMBL:ENSG00000052802 MSMO1

HGNC:10545 MSMO1

KEGG:hsa:6307 MSMO1

Monarch:6307 MSMO1

NCBI Gene:6307 MSMO1

OMIM:607545 MSMO1

UCSC:Q15800 MSMO1

Reference Transcript

Other Identifiers

11740092_x_at

11741012_a_at

11757764_s_at

11763767_at

16972155

209146_PM_at

209146_at

2740408

2750595

2750596

2750597

2750604

2750605

2750606

2750609

2750610

2750611

2750612

2750616

2750617

2750618

2750619

2750620

33369_at

33370_r_at

6307

8098195

88287_at

A_14_P110787

A_14_P125113

A_23_P110184

GE62979

GO:0000254

GO:0003824

GO:0005506

GO:0005515

GO:0005783

GO:0005789

GO:0005886

GO:0006629

GO:0006631

GO:0006695

GO:0008202

GO:0008610

GO:0016020

GO:0016126

GO:0016491

GO:0043226

HMNXSV003021865

Hs.239926.0.A2_3p_at

ILMN_1689842

ILMN_1720889

ILMN_2402499

PH_hs_0028315

TC04000828.hg

U60205_at

Inferred To

MSMO1 [endoplasmic reticulum membrane] (Bos taurus)

MSMO1 [endoplasmic reticulum membrane] (Canis familiaris)

MSMO1 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

MSMO1 [endoplasmic reticulum membrane] (Gallus gallus)

MSMO1 [endoplasmic reticulum membrane] (Sus scrofa)

erg25 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

msmo1 [endoplasmic reticulum membrane] (Danio rerio)

msmo1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Msmo1 [endoplasmic reticulum membrane] (Mus musculus)

Msmo1 [endoplasmic reticulum membrane] (Rattus norvegicus)

ERG25 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

XP_005263233.1, NP_006736.1, NP_001017369.1, XP_054206679.1

OpenTargets

ENSG00000052802

ENSEMBL

ENSP00000261507, ENSG00000052802, ENST00000261507, ENSP00000377361, ENST00000393766

IntEnz

1.14.18.9

HPA

ENSG00000052802-MSMO1

GeneCards

MSMO1

PRO

Q15800

Pharos - Targets

Q15800

Orphanet

MSMO1

GlyGen

Q15800

HMDB Protein

HMDBP00263

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.556	3
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.556	3
UniProt:P09601 HMOX1	4	HMOX1 [cytosol] (R-HSA-9609901) HMOX1 [endoplasmic reticulum membrane] (R-HSA-189395) HMOX1 [mitochondrial outer membrane] (R-HSA-9708524) HMOX1 [nucleoplasm] (R-HSA-9708567)	0.556	3
UniProt:P50281 MMP14	4	MMP14(21-582) [Golgi lumen] (R-HSA-1604689) MMP14 [Golgi lumen] (R-HSA-1604724) MMP14 [plasma membrane] (R-HSA-1442472) MMP14 [Golgi membrane] (R-HSA-9858808)	0.556	3
UniProt:Q9UKR5 ERG28			0.556	3
UniProt:P0DN84 DWORF			0.556	3
UniProt:Q9NV12 TM140			0.556	3
UniProt:Q6PI78 TMM65			0.556	3
UniProt:Q9NWH2 TM242			0.556	3
UniProt:Q6ZVE7 GOT1A			0.556	3
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.556	3
UniProt:Q96LL9 DJC30			0.556	3
UniProt:Q6NT55 CYP4F22	5	CYP4F22 [endoplasmic reticulum membrane] (R-HSA-211056) CYP4F22 H436D [endoplasmic reticulum membrane] (R-HSA-5602276) CYP4F22 W521* [endoplasmic reticulum membrane] (R-HSA-5602291) CYP4F22 H435Y [endoplasmic reticulum membrane] (R-HSA-5602287) CYP4F22 R243H [endoplasmic reticulum membrane] (R-HSA-5602296)	0.556	3
UniProt:Q9HC97 GPR35	1	GPR35 [plasma membrane] (R-HSA-3295332)	0.547	2
UniProt:Q96G97 BSCL2			0.527	2
UniProt:Q86VR2 RETR3			0.527	2
UniProt:Q86T26 TM11B			0.527	3
UniProt:A1L0T0 HACL2			0.527	2
UniProt:Q16581 C3AR1	3	C3AR1 [plasma membrane] (R-HSA-444727) C3AR1 [specific granule membrane] (R-HSA-6799516) C3AR1 [azurophil granule membrane] (R-HSA-6799517)	0.527	2
UniProt:Q92633 LPAR1	1	LPAR1 [plasma membrane] (R-HSA-419354)	0.527	2
UniProt:P32241 VIPR1	1	VIPR1 [plasma membrane] (R-HSA-420157)	0.527	2
UniProt:P10253 GAA	8	GAA (123-?) [lysosomal lumen] (R-HSA-5357560) GAA (204-?) [lysosomal lumen] (R-HSA-5357544) GAA [azurophil granule membrane] (R-HSA-6800877) GAA [plasma membrane] (R-HSA-6801041) GAA [tertiary granule membrane] (R-HSA-6801021) GAA [ficolin-1-rich granule membrane] (R-HSA-6800913) GAA M318T [lysosomal lumen] (R-HSA-5357607) GAA E521K [lysosomal lumen] (R-HSA-5357598)	0.527	2

Cite Us!