Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
SLCO1B1 [plasma membrane]
Stable Identifier
R-HSA-194133
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
OATP-C, Solute carrier organic anion transporter family member 1B1
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Atorvastatin ADME (Homo sapiens)
SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Homo sapiens)
SLCO1B1,1B3,2B1-3 [plasma membrane] (Homo sapiens)
SLCO1B1 [plasma membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Recycling of bile acids and salts (Homo sapiens)
SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Homo sapiens)
SLCO1B1 [plasma membrane] (Homo sapiens)
Metabolism of porphyrins (Homo sapiens)
Heme degradation (Homo sapiens)
SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)
SLCO1B1 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of organic anions (Homo sapiens)
SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Homo sapiens)
SLCO1B1 [plasma membrane] (Homo sapiens)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Homo sapiens)
SLCO1B1 [plasma membrane] (Homo sapiens)
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Homo sapiens)
SLCOs, SLC16A2 dimer [plasma membrane] (Homo sapiens)
SLCO1B1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y6L6 SLCO1B1
Gene Names
SLCO1B1, LST1, OATP1B1, OATP2, OATPC, SLC21A6
Chain
chain:1-691
Reference Genes
BioGPS Gene:10599 SLCO1B1
COSMIC (genes):SLCO1B1 SLCO1B1
CTD Gene:10599 SLCO1B1
dbSNP Gene:10599 SLCO1B1
ENSEMBL:ENSG00000134538.3 SLCO1B1
HGNC:10959 SLCO1B1
KEGG Gene (Homo sapiens):10599 SLCO1B1
Monarch:10599 SLCO1B1
NCBI Gene:10599 SLCO1B1
OMIM:604843 SLCO1B1
UCSC:Q9Y6L6 SLCO1B1
Reference Transcript
RefSeq:NM_006446.4 SLCO1B1
Other Identifiers
0002640142
10599
11739848_at
16749077
210366_PM_at
210366_at
3407646
3407685
3407708
3407710
3407711
3407713
3407715
3407716
3407717
3407718
3407719
3407720
3407723
3407724
3407725
3407726
3407729
3407732
3407733
3407734
3407735
3407739
3407740
3407741
3407745
35570_at
7954356
A_14_P114848
A_23_P128254
GE55225
GO:0005215
GO:0005515
GO:0005886
GO:0005887
GO:0006805
GO:0006811
GO:0008514
GO:0015125
GO:0015132
GO:0015347
GO:0015349
GO:0015711
GO:0015721
GO:0016020
GO:0016021
GO:0016323
GO:0022857
GO:0042167
GO:0043252
GO:0055085
GO:0070327
HMNXSV003014356
ILMN_1771118
ILMN_2084745
PH_hs_0038723
TC12002283.hg
TC12003240.hg
g5006264_3p_at
Participates
as a member of
SLCOs, SLC16A2 dimer [plasma membrane] (Homo sapiens)
SLCO1B1,1B3,2B1-3 [plasma membrane] (Homo sapiens)
Other forms of this molecule
SLCO1B1 R580* [plasma membrane]
SLCO1B1 R253* [plasma membrane]
Inferred To
slco1b3 [plasma membrane]
(Xenopus tropicalis)
Oatp30B [plasma membrane]
(Drosophila melanogaster)
SLCO1B1 [plasma membrane]
(Caenorhabditis elegans)
SLCO1B1 [plasma membrane]
(Canis familiaris)
SLCO1B1 [plasma membrane]
(Danio rerio)
SLCO1B3 [plasma membrane]
(Bos taurus)
SLCO1B3 [plasma membrane]
(Gallus gallus)
SLCO1B3 [plasma membrane]
(Sus scrofa)
Homologues of SLCO1B1 [plasma membrane]
(Danio rerio)
Slco1b2 [plasma membrane]
(Mus musculus)
Slco1b2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_006437.3
ZINC - World Drugs
SO1B1_HUMAN
Guide to Pharmacology - Targets
1220
OpenTargets
ENSG00000134538
ZINC - FDA approved
SO1B1_HUMAN
ZINC - Substances
SO1B1_HUMAN
ZINC - Biogenic
SO1B1_HUMAN
ZINC target
Q9Y6L6
PRO
Q9Y6L6
ZINC - Investigational
SO1B1_HUMAN
ZINC - Metabolites
SO1B1_HUMAN
HPA
ENSG00000134538-SLCO1B1
GeneCards
Q9Y6L6
Ensembl
ENST00000256958
,
ENSG00000134538
,
ENSP00000256958
Pharos - Targets
Q9Y6L6
Orphanet
19458
ZINC - Predictions - Purchasable
SO1B1_HUMAN
HMDB Protein
HMDBP00454
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text