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SLCO1B3 [plasma membrane]
Stable Identifier
R-HSA-194075
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
OATP-8, Solute carrier organic anion transporter family member 1B3
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Atorvastatin ADME (Homo sapiens)
SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Homo sapiens)
SLCO1B1,1B3,2B1-3 [plasma membrane] (Homo sapiens)
SLCO1B3 [plasma membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Recycling of bile acids and salts (Homo sapiens)
SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Homo sapiens)
SLCO1B3 [plasma membrane] (Homo sapiens)
Metabolism of porphyrins (Homo sapiens)
Heme degradation (Homo sapiens)
SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)
SLCO1B3 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of organic anions (Homo sapiens)
SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Homo sapiens)
SLCO1B3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NPD5 SLCO1B3
Gene Names
SLCO1B3, LST2, OATP1B3, OATP8, SLC21A8
Chain
chain:1-702
Reference Genes
BioGPS Gene:28234 SLCO1B3
COSMIC (genes):SLCO1B3 SLCO1B3
CTD Gene:28234 SLCO1B3
dbSNP Gene:28234 SLCO1B3
ENSEMBL:ENSG00000111700 SLCO1B3
ENSEMBL_homo_sapiens_GENE:ENSG00000111700.13 SLCO1B3
HGNC:10961 SLCO1B3
KEGG Gene (Homo sapiens):28234 SLCO1B3
Monarch:28234 SLCO1B3
NCBI Gene:28234 SLCO1B3
OMIM:605495 SLCO1B3
UCSC:Q9NPD5 SLCO1B3
Reference Transcript
RefSeq:NM_019844.3 SLCO1B3
Other Identifiers
11732569_at
16749036
206354_PM_at
206354_at
28234
3407630
3407631
3407632
3407633
3407639
3407640
3407643
3407644
3407645
3407646
3407649
3407650
3407652
3407653
3407655
3407656
3407657
3407660
3407663
3407666
3407667
3407668
3407686
3407689
3407690
3407693
7954330
A_14_P102835
A_14_P108697
A_14_P133603
A_23_P105475
A_33_P3364089
GE82482
GO:0004867
GO:0005215
GO:0005515
GO:0005886
GO:0006805
GO:0006811
GO:0006869
GO:0008514
GO:0009925
GO:0015125
GO:0015347
GO:0015711
GO:0015721
GO:0016020
GO:0016323
GO:0022857
GO:0030414
GO:0042167
GO:0043252
GO:0055085
GO:0098772
HMNXSV003006405
ILMN_1687319
PH_hs_0030139
TC12002282.hg
g9790232_3p_at
Participates
as a member of
SLCO1B1,1B3,2B1-3 [plasma membrane] (Homo sapiens)
Other forms of this molecule
SLCO1B3 I562* [plasma membrane]
Inferred To
slco1b3 [plasma membrane]
(Xenopus tropicalis)
SLCO1B2 [plasma membrane]
(Canis familiaris)
SLCO1B2 [plasma membrane]
(Sus scrofa)
Homologues of SLCO1B3 [plasma membrane]
(Danio rerio)
Oatp30B [plasma membrane]
(Drosophila melanogaster)
SLCO1B3 [plasma membrane]
(Bos taurus)
SLCO1B3 [plasma membrane]
(Caenorhabditis elegans)
SLCO1B3 [plasma membrane]
(Gallus gallus)
slco1c1 [plasma membrane]
(Danio rerio)
slco1e1 [plasma membrane]
(Danio rerio)
Slco1b2 [plasma membrane]
(Mus musculus)
Slco1b2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_062818.1
ZINC - World Drugs
SO1B3_HUMAN
Guide to Pharmacology - Targets
1221
OpenTargets
ENSG00000111700
ZINC - FDA approved
SO1B3_HUMAN
ZINC - Substances
SO1B3_HUMAN
ZINC - Biogenic
SO1B3_HUMAN
ZINC target
Q9NPD5
PRO
Q9NPD5
PDB
8PG0
ZINC - Investigational
SO1B3_HUMAN
ZINC - Metabolites
SO1B3_HUMAN
GeneCards
Q9NPD5
HPA
ENSG00000111700-SLCO1B3
Ensembl
ENSP00000261196
,
ENST00000261196
,
ENSG00000111700
,
ENST00000381545
,
ENSP00000370956
Pharos - Targets
Q9NPD5
ZINC - Predictions - Purchasable
SO1B3_HUMAN
Orphanet
20820
HMDB Protein
HMDBP00446
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