Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
SLCO1B3 [plasma membrane]
Stable Identifier
R-HSA-194075
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
OATP-8, Solute carrier organic anion transporter family member 1B3
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Atorvastatin ADME (Homo sapiens)
SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Homo sapiens)
SLCO1B1,1B3,2B1-3 [plasma membrane] (Homo sapiens)
SLCO1B3 [plasma membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Recycling of bile acids and salts (Homo sapiens)
SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Homo sapiens)
SLCO1B3 [plasma membrane] (Homo sapiens)
Metabolism of porphyrins (Homo sapiens)
Heme degradation (Homo sapiens)
SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)
SLCO1B3 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of organic anions (Homo sapiens)
SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Homo sapiens)
SLCO1B3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NPD5 SLCO1B3
Gene Names
SLCO1B3, LST2, OATP1B3, OATP8, SLC21A8
Chain
chain:1-702
Reference Genes
BioGPS Gene:28234 SLCO1B3
COSMIC (genes):SLCO1B3 SLCO1B3
CTD Gene:28234 SLCO1B3
dbSNP Gene:28234 SLCO1B3
ENSEMBL:ENSG00000111700 SLCO1B3
HGNC:10961 SLCO1B3
KEGG Gene (Homo sapiens):28234 SLCO1B3
Monarch:28234 SLCO1B3
NCBI Gene:28234 SLCO1B3
OMIM:605495 SLCO1B3
UCSC:Q9NPD5 SLCO1B3
Reference Transcript
RefSeq:NM_019844.3 SLCO1B3
Other Identifiers
0005130193
11732569_at
16749036
206354_at
28234
3407630
3407631
3407632
3407633
3407639
3407640
3407643
3407644
3407645
3407646
3407649
3407650
3407652
3407653
3407655
3407656
3407657
3407660
3407663
3407666
3407667
3407668
3407686
3407689
3407690
3407693
7954330
A_14_P102835
A_14_P108697
A_14_P133603
A_23_P105475
A_33_P3364089
GE82482
GO:0003674
GO:0005515
GO:0005575
GO:0005886
GO:0005887
GO:0006810
GO:0006811
GO:0008150
GO:0008514
GO:0009056
GO:0015125
GO:0015347
GO:0015711
GO:0015721
GO:0016020
GO:0016021
GO:0016323
GO:0022857
GO:0034641
GO:0042167
GO:0043252
GO:0055085
HMNXSV003006405
ILMN_1687319
PH_hs_0030139
TC12002282.hg
g9790232_3p_at
Participates
as a member of
SLCO1B1,1B3,2B1-3 [plasma membrane] (Homo sapiens)
Other forms of this molecule
SLCO1B3 I562* [plasma membrane]
Inferred To
slco1f4 [plasma membrane]
(Danio rerio)
Homologues of SLCO1B3 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLCO1B3 [plasma membrane]
(Danio rerio)
SLCO1B3 [plasma membrane]
(Bos taurus)
SLCO1B3 [plasma membrane]
(Caenorhabditis elegans)
SLCO1B3 [plasma membrane]
(Canis familiaris)
SLCO1B3 [plasma membrane]
(Gallus gallus)
SLCO1B3 [plasma membrane]
(Sus scrofa)
SLCO1B3 [plasma membrane]
(Xenopus tropicalis)
slco1f1 [plasma membrane]
(Danio rerio)
Slco1b2 [plasma membrane]
(Mus musculus)
Slco1b2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_062818.1
ZINC - World Drugs
SO1B3_HUMAN
Guide to Pharmacology - Targets
1221
OpenTargets
ENSG00000111700
ZINC - FDA approved
SO1B3_HUMAN
ZINC - Substances
SO1B3_HUMAN
ZINC target
Q9NPD5
ZINC - Biogenic
SO1B3_HUMAN
PRO
Q9NPD5
GlyGen
Q9NPD5
ZINC - Investigational
SO1B3_HUMAN
ZINC - Metabolites
SO1B3_HUMAN
GeneCards
Q9NPD5
HPA
ENSG00000111700-SLCO1B3
Ensembl
ENSG00000111700
,
ENST00000261196
,
ENST00000381545
,
ENSP00000261196
,
ENSP00000370956
Pharos - Targets
Q9NPD5
ZINC - Predictions - Purchasable
SO1B3_HUMAN
Orphanet
20820
HMDB Protein
HMDBP00446
© 2022
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
