11DCORST translocates from cytosol to mitochondrial matrix

Stable Identifier
R-HSA-193996
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, mitochondrial matrix
Synonyms
11-deoxycorticosterone translocates from the cytosol to the mitochondrial matrix
ReviewStatus
5/5
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11DCORST translocates from cytosol to mitochondrial matrix
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11-deoxycorticosterone is synthesized in a reaction at the endoplasmic reticulum membrane and is further metabolized, ultimately to yield aldosterone, in reactions catalyzed by mitochondrial enzymes. The means by which 11-deoxycorticosterone translocates into the mitochondrial matrix, however, is unknown.
Literature References
PubMed ID Title Journal Year
15583024 Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones

Payne, AH, Hales, DB

Endocr Rev 2004
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Authored
Jassal, B  (2008-10-01)
Reviewed
D'Eustachio, P  (2007-04-21)
Created
Jassal, B  (2007-03-06)
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