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11DCORST translocates from cytosol to mitochondrial matrix
Stable Identifier
R-HSA-193996
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
,
mitochondrial matrix
Synonyms
11-deoxycorticosterone translocates from the cytosol to the mitochondrial matrix
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Metabolism of steroid hormones (Homo sapiens)
Mineralocorticoid biosynthesis (Homo sapiens)
11DCORST translocates from cytosol to mitochondrial matrix (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
11-deoxycorticosterone is synthesized in a reaction at the endoplasmic reticulum membrane and is further metabolized, ultimately to yield aldosterone, in reactions catalyzed by mitochondrial enzymes. The means by which 11-deoxycorticosterone translocates into the mitochondrial matrix, however, is unknown.
Literature References
PubMed ID
Title
Journal
Year
15583024
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
Payne, AH
,
Hales, DB
Endocr Rev
2004
Participants
Input
11DCORST [cytosol]
Output
11DCORST [mitochondrial matrix]
Participates
as an event of
Mineralocorticoid biosynthesis (Homo sapiens)
Event Information
Go Biological Process
import into the mitochondrion (0170036)
Authored
Jassal, B (2008-10-01)
Reviewed
D'Eustachio, P (2007-04-21)
Created
Jassal, B (2007-03-06)
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