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CYP11B1 [mitochondrial inner membrane]
Stable Identifier
R-HSA-193978
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Cytochrome P450 11B1, CPN1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP11B1 oxidises 11DCORT (Homo sapiens)
Cytochrome P450 (CYP11B1 based) [mitochondrial inner membrane] (Homo sapiens)
CYP11B1 [mitochondrial inner membrane] (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Metabolism of steroid hormones (Homo sapiens)
Glucocorticoid biosynthesis (Homo sapiens)
CYP11B1 oxidises 11DCORT (Homo sapiens)
Cytochrome P450 (CYP11B1 based) [mitochondrial inner membrane] (Homo sapiens)
CYP11B1 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15538 CYP11B1
Gene Names
CYP11B1, S11BH
Chain
transit peptide:1-24, chain:25-503
Reference Genes
BioGPS Gene:1584 CYP11B1
COSMIC (genes):CYP11B1 CYP11B1
CTD Gene:1584 CYP11B1
dbSNP Gene:1584 CYP11B1
ENSEMBL:ENSG00000160882 CYP11B1
ENSEMBL_homo_sapiens_GENE:ENSG00000160882.13 CYP11B1
HGNC:2591 CYP11B1
KEGG Gene (Homo sapiens):1584 CYP11B1
Monarch:1584 CYP11B1
NCBI Gene:1584 CYP11B1
OMIM:610613 CYP11B1
UCSC:P15538 CYP11B1
Reference Transcript
RefSeq:NM_000497.3 CYP11B1
RefSeq:NM_001026213.1 CYP11B1
Other Identifiers
11734127_a_at
11734128_a_at
1412_g_at
1552493_PM_s_at
1552493_s_at
1584
214610_PM_at
214610_at
3157216
3157218
3157219
3157220
3157221
3157222
3157223
3157225
3157226
3157228
3157231
3157232
3157233
3157234
3157235
3157237
3157238
3157239
3157247
3157249
3157251
3157255
3157257
34548_at
34549_g_at
79018_at
8153363
A_23_P168928
A_24_P329424
GE59810
GO:0002376
GO:0003013
GO:0003824
GO:0004497
GO:0004507
GO:0005506
GO:0005739
GO:0005743
GO:0006629
GO:0006694
GO:0006700
GO:0006704
GO:0006955
GO:0008202
GO:0008203
GO:0008217
GO:0016020
GO:0016125
GO:0016491
GO:0016705
GO:0020037
GO:0032342
GO:0032870
GO:0034650
GO:0034651
GO:0035865
GO:0042593
GO:0043226
GO:0046872
GO:0047783
GO:0071375
GO:1901615
HMNXSV003012949
HMNXSV003041760
Hs.301118.0.S2_3p_at
Hs2.377912.1.S1_3p_s_at
ILMN_1801917
ILMN_2358436
M32879_at
M32879_s_at
PH_hs_0035658
TC08001708.hg
Participates
as a member of
Cytochrome P450 (CYP11B1 based) [mitochondrial inner membrane] (Homo sapiens)
Other forms of this molecule
CYP11B1 R448H [mitochondrial inner membrane]
CYP11B1 R374Q [mitochondrial inner membrane]
CYP11B1 T318M [mitochondrial inner membrane]
CYP11B1 R448C [mitochondrial inner membrane]
CYP11B1 E371G [mitochondrial inner membrane]
CYP11B1 A331V [mitochondrial inner membrane]
Inferred To
Homologues of CYP11B1 [mitochondrial inner membrane]
(Bos taurus)
Homologues of CYP11B1 [mitochondrial inner membrane]
(Mus musculus)
Homologues of CYP11B1 [mitochondrial inner membrane]
(Rattus norvegicus)
CYP11B1 [mitochondrial inner membrane]
(Bos taurus)
CYP11B1 [mitochondrial inner membrane]
(Mus musculus)
CYP11B1 [mitochondrial inner membrane]
(Rattus norvegicus)
CYP11B2 [mitochondrial inner membrane]
(Canis familiaris)
CYP11B2 [mitochondrial inner membrane]
(Mus musculus)
CYP11B2 [mitochondrial inner membrane]
(Rattus norvegicus)
CYP11B2 [mitochondrial inner membrane]
(Sus scrofa)
LOC101731070 [mitochondrial inner membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000488.3
,
NP_001021384.1
ZINC - World Drugs
C11B1_HUMAN
Guide to Pharmacology - Targets
1359
OpenTargets
ENSG00000160882
ZINC - FDA approved
C11B1_HUMAN
ZINC - Substances
C11B1_HUMAN
ZINC target
P15538
PRO
P15538
PDB
6M7X
,
7E7F
ZINC - Investigational
C11B1_HUMAN
HPA
ENSG00000160882-CYP11B1
GeneCards
P15538
Ensembl
ENSP00000428043
,
ENST00000292427
,
ENST00000517471
,
ENSP00000292427
,
ENSG00000160882
Pharos - Targets
P15538
Orphanet
15834
ZINC - Predictions - Purchasable
C11B1_HUMAN
HMDB Protein
HMDBP00445
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