Part of the ICD migrates to the nucleus

Stable Identifier
R-HSA-193702
Type
Reaction
Species
Homo sapiens
Compartment
nuclear envelope
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Part of the ICD migrates to the nucleus
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A portion of the p75NTR ICD produced by gamma-secretase cleavage moves to the nucleus where it may participate in transcriptional regulation.

Literature References
PubMed ID Title Journal Year
12843241 Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability

Amieux, PS, Schecterson, LC, Wiley, JC, Hudson, M, Kanning, KC, Bothwell, M

J Neurosci 2003
Participants
Input
Output
Participates
as an event of
Orthologous Events
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Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Friedman, WJ  (2008-05-20)
Chao, MV  (2008-05-28)
Created
Jassal, B  (2007-02-23)
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