Reactome | MYD88 dissociates

MYD88 dissociates

Stable Identifier

R-HSA-193665

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cytosol, plasma membrane

ReviewStatus

5/5

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After recruiting IRAK, MYD88 leaves the receptor complex. The amount of MYD88 that associates with p75 peaks at 1 min of NGF treatment and declines thereafter.

Literature References

PubMed ID	Title	Journal	Year
9575168	MyD88, an adapter protein involved in interleukin-1 signaling Di Marco, F, Burns, K, French, L, Martinon, F, Esslinger, C, Schneider, P, Bodmer, JL, Tschopp, J, Pahl, H	J Biol Chem	1998