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PRDM4 translocates to the nucleus
Stable Identifier
R-HSA-193661
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
p75NTR negatively regulates cell cycle via SC1 (Homo sapiens)
PRDM4 translocates to the nucleus (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
PRDM4 is found in the cytoplasm. Following binding of NGF to p75NTR, after 1 hour of NGF treatment, PRDM4 is redistributed from the cytoplasm to the nucleus. The relocalisation of PRDM4 appears to be specific for NGF, as it is not affected by BDNF or NT3.
Participants
Input
PRDM4 [cytosol]
(Homo sapiens)
Output
PRDM4 [nucleoplasm]
(Homo sapiens)
Participates
as an event of
p75NTR negatively regulates cell cycle via SC1 (Homo sapiens)
Inferred From
Prdm4 translocates to the nucleus (Rattus norvegicus)
Authored
Nasi, S (2006-10-10)
Annibali, D (2006-10-10)
Reviewed
Friedman, WJ (2008-05-20)
Chao, MV (2008-05-28)
Created
Jassal, B (2007-02-23)
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