p75NTR binds to NADE

Stable Identifier
R-HSA-193650
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
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p75NTR binds to NADE
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The NADE protein interacts with p75NTR to mediate cell death. The interaction is mediated by NADE NES (nuclear export signal), also responsible for self-association of NADE (Mukai J et al, 2002).

Literature References
PubMed ID Title Journal Year
10764727 NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR

Mukai, J, Hachiya, T, Shoji-Hoshino, S, Kimura, MT, Nadano, D, Suvanto, P, Hanaoka, T, Li, Y, Irie, S, Greene, LA, Sato, TA

J Biol Chem 2000
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Orthologous Events
p75NTR binds to NADE (Bos taurus)
p75NTR binds to NADE (Canis familiaris)
p75NTR binds to NADE (Mus musculus)
p75NTR binds to NADE (Rattus norvegicus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Friedman, WJ  (2008-05-20)
Chao, MV  (2008-05-28)
Created
Jassal, B  (2007-02-23)