Reactome | p75NTR binds to NADE

p75NTR binds to NADE

Stable Identifier

R-HSA-193650

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol, plasma membrane

ReviewStatus

5/5

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The NADE protein interacts with p75NTR to mediate cell death. The interaction is mediated by NADE NES (nuclear export signal), also responsible for self-association of NADE (Mukai J et al, 2002).

Literature References

PubMed ID	Title	Journal	Year
10764727	NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR Mukai, J, Hachiya, T, Shoji-Hoshino, S, Kimura, MT, Nadano, D, Suvanto, P, Hanaoka, T, Li, Y, Irie, S, Greene, LA, Sato, TA	J Biol Chem	2000