PRDM4 (SC1) binds to p75NTR

Stable Identifier
R-HSA-193643
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
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PRDM4 (SC1) binds to p75NTR
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PRDM4, usually named SC1, for Schwann Cell factor 1, is a zinc finger protein that functions as a repressor of transcription. It is present in many tissues, and abundant in brain. It interacts with the NGF:p75NTR complex to signal cell cycle arrest. It is unclear whether it already forms a complex with p75NTR before NGF binding to p75.

Participants
Input
Output
Participant Of
hasEvent
Inferred From
Prdm4 (Sc1) binds to p75NTR (Rattus norvegicus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Friedman, WJ  (2008-05-20)
Chao, MV  (2008-05-28)
Created
Jassal, B  (2007-02-23)