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Pregnenolone translocates from the mitochondrial matrix to the cytosol
Stable Identifier
R-HSA-193097
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
mitochondrial matrix
,
cytosol
ReviewStatus
5/5
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Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Metabolism of steroid hormones (Homo sapiens)
Pregnenolone biosynthesis (Homo sapiens)
Pregnenolone translocates from the mitochondrial matrix to the cytosol (Homo sapiens)
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Inferred from rat: Pregenolone is translocated from the mitochondrial matrix to the cytosol. Neither transport proteins to mediate its movement across the inner mitochondrial membrane nor carrier proteins to facilitate its movement in the cytosol have been identified, and the mechanism of this translocation is unknown (Ray and Strott 1991).
Literature References
PubMed ID
Title
Journal
Year
6264249
Cytosol stimulation of pregnenolone synthesis by isolated adrenal mitochondria
Ray, P
,
Strott, CA
Life Sci.
1981
Participants
Input
PREG [mitochondrial matrix]
Output
PREG [cytosol]
Participates
as an event of
Pregnenolone biosynthesis (Homo sapiens)
Event Information
Go Biological Process
export from the mitochondrion (0170037)
Authored
Jassal, B (2008-10-01)
Reviewed
D'Eustachio, P (2007-04-21)
Created
Jassal, B (2007-02-13)
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