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FGFR2b short [plasma membrane]
Stable Identifier
R-HSA-192601
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Fibroblast growth factor receptor 2b short, FGFR2-18, FGFR2 isoform 18
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR2 in disease (Homo sapiens)
FGFR2 mutant receptor activation (Homo sapiens)
Signaling by FGFR2 IIIa TM (Homo sapiens)
FGFR2IIIa TM binds ligand and full length receptors to inhibit signaling (Homo sapiens)
FGFR2IIIa TM:FGF1,2:FGFR2b, FGFR2c [plasma membrane] (Homo sapiens)
FGFR2b, FGFR2c [plasma membrane] (Homo sapiens)
FGFR2b [plasma membrane] (Homo sapiens)
FGFR2b short [plasma membrane] (Homo sapiens)
FGFR2b, FGFR2c [plasma membrane] (Homo sapiens)
FGFR2b [plasma membrane] (Homo sapiens)
FGFR2b short [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by FGFR (Homo sapiens)
Signaling by FGFR2 (Homo sapiens)
FGFR2 ligand binding and activation (Homo sapiens)
FGFR2b ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR2b (Homo sapiens)
FGFR2b homodimer bound to FGF [plasma membrane] (Homo sapiens)
FGFR2b short homodimer bound to FGF [plasma membrane] (Homo sapiens)
FGFR2b short homodimer [plasma membrane] (Homo sapiens)
FGFR2b short [plasma membrane] (Homo sapiens)
FGFR2b binds to FGF (Homo sapiens)
FGFR2b [plasma membrane] (Homo sapiens)
FGFR2b short [plasma membrane] (Homo sapiens)
FGFR2b homodimer bound to FGF [plasma membrane] (Homo sapiens)
FGFR2b short homodimer bound to FGF [plasma membrane] (Homo sapiens)
FGFR2b short homodimer [plasma membrane] (Homo sapiens)
FGFR2b short [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P21802-18 FGFR2
Gene Names
FGFR2, BEK, KGFR, KSAM
Participates
as a member of
FGFR2b [plasma membrane] (Homo sapiens)
as a component of
FGFR2b short homodimer [plasma membrane] (Homo sapiens)
Other forms of this molecule
Phosphorylated Fibroblast growth factor receptor 2b short [plasma membrane]
Inferred To
FGFR2b short [plasma membrane]
(Bos taurus)
FGFR2b short [plasma membrane]
(Caenorhabditis elegans)
FGFR2b short [plasma membrane]
(Canis familiaris)
FGFR2b short [plasma membrane]
(Danio rerio)
FGFR2b short [plasma membrane]
(Drosophila melanogaster)
FGFR2b short [plasma membrane]
(Gallus gallus)
FGFR2b short [plasma membrane]
(Mus musculus)
FGFR2b short [plasma membrane]
(Rattus norvegicus)
Homologues of FGFR2b short [plasma membrane]
(Drosophila melanogaster)
Interactors (30)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P09038 FGF2
1
FGF2(10-155) [extracellular region]
(R-HSA-189898)
0.779
5
UniProt:P51812 RPS6KA3
7
p-S227,T365,S369,S386,T577,T737-RPS6KA3 [nucleoplasm]
(R-HSA-444286)
p-T365,S369,S386,T577,T737-RPS6KA3 [cytosol]
(R-HSA-9619989)
p-S227,T365,S369,S386,T577,T737-RPS6KA3 [cytosol]
(R-HSA-9619872)
p-T365,S369,T577-RPS6KA3 [cytosol]
(R-HSA-9619959)
RPS6KA3 [cytosol]
(R-HSA-444250)
p-4S,T231,T365-RPS6KA3 [nucleoplasm]
(R-HSA-199830)
RPS6KA3 [nucleoplasm]
(R-HSA-199869)
0.745
5
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.735
6
ChEBI:73280 SSR
0.683
8
UniProt:P05230 FGF1
1
FGF1 [extracellular region]
(R-HSA-189856)
0.675
3
UniProt:P11362 FGFR1
9
FGFR1 [plasma membrane]
(R-HSA-9756433)
p-8Y- FGFR1 R576W [plasma membrane]
(R-HSA-2023361)
p-8Y-FGFR1 N546K [plasma membrane]
(R-HSA-2023358)
p-8Y-FGFR1 K656E [plasma membrane]
(R-HSA-2023356)
p-6Y-FGFR1(22-763):TACC1(571-805) fusion [plasma membrane]
(R-HSA-8853142)
FGFR1 R576W [plasma membrane]
(R-HSA-2011844)
FGFR1 N546K [plasma membrane]
(R-HSA-1614377)
FGFR1 K656E [plasma membrane]
(R-HSA-1614373)
FGFR1(22-763):TACC1(571-805) fusion [plasma membrane]
(R-HSA-8853241)
0.623
3
UniProt:O15520 FGF10
1
FGF10 [extracellular region]
(R-HSA-189869)
0.571
2
UniProt:P19174 PLCG1
6
p-4Y-PLCG1 [plasma membrane]
(R-HSA-167679)
PLCG1 [cytosol]
(R-HSA-202320)
PLCG1 [plasma membrane]
(R-HSA-167682)
p-Y771,Y783,Y1254-PLCG1 [cytosol]
(R-HSA-202357)
p-Y771,Y783-PLCG1 [plasma membrane]
(R-HSA-1169084)
p-Y-PLCG1 [cytosol]
(R-HSA-9029082)
0.528
3
UniProt:Q3MIR4 CC50B
0.527
2
UniProt:O60637 TSN3
0.527
2
UniProt:Q96LL9 DJC30
0.527
2
UniProt:Q6P047 CH074
0.527
2
UniProt:Q99732 LITAF
0.527
2
UniProt:Q8N7X8 SIGL1
0.527
2
UniProt:Q5T9A4 ATAD3B
3
ATAD3B [secretory granule membrane]
(R-HSA-6801313)
ATAD3B [plasma membrane]
(R-HSA-6806518)
ATAD3B [ficolin-1-rich granule membrane]
(R-HSA-6801277)
0.527
2
UniProt:Q96HB5 CC120
0.527
2
UniProt:Q8IWX8 CHERP
1
CHERP [nucleoplasm]
(R-HSA-8865901)
0.527
2
UniProt:Q92551 IP6K1
2
IP6K1 [cytosol]
(R-HSA-1604591)
IP6K1 [nucleoplasm]
(R-HSA-2023952)
0.527
2
UniProt:Q6P995 F171B
0.527
2
UniProt:P34741 SDC2
20
HS(4)-SDC2 [plasma membrane]
(R-HSA-2076683)
HS(6)-SDC2 [plasma membrane]
(R-HSA-2076661)
HS(2)-SDC2 [plasma membrane]
(R-HSA-2076644)
HS(1)-SDC2 [plasma membrane]
(R-HSA-2076643)
HS(3)-SDC2 [plasma membrane]
(R-HSA-2076631)
HS(5)-SDC2 [plasma membrane]
(R-HSA-2076665)
SDC2 [endoplasmic reticulum lumen]
(R-HSA-8956741)
p-SDC2 [endoplasmic reticulum lumen]
(R-HSA-8956945)
XylS-SDC2 [Golgi lumen]
(R-HSA-2064109)
Gal-Xyl-SDC2 [Golgi lumen]
(R-HSA-2064132)
SDC2 [Golgi lumen]
(R-HSA-2054101)
Gal-Gal-Xyl-SDC2 [Golgi lumen]
(R-HSA-2063988)
GlcA-Gal-Gal-Xyl-SDC2 [Golgi lumen]
(R-HSA-2063997)
HS(3)-SDC2 [Golgi lumen]
(R-HSA-2076443)
HS(4)-SDC2 [Golgi lumen]
(R-HSA-2076356)
HS(2)-SDC2 [Golgi lumen]
(R-HSA-2076603)
HS(1)-SDC2 [Golgi lumen]
(R-HSA-2076607)
Heparan(4)-SDC2 [Golgi lumen]
(R-HSA-2076576)
Heparan(3)-SDC2 [Golgi lumen]
(R-HSA-2076361)
Heparan(2)-SDC2 [Golgi lumen]
(R-HSA-2076397)
0.527
2
UniProt:Q92575 UBXN4
0.527
2
UniProt:Q96L94 SNX22
0.527
2
UniProt:P01033 TIMP1
4
TIMP1 [platelet alpha granule lumen]
(R-HSA-349745)
p-TIMP1 [endoplasmic reticulum lumen]
(R-HSA-8957082)
TIMP1 [endoplasmic reticulum lumen]
(R-HSA-8956691)
TIMP1 [extracellular region]
(R-HSA-349743)
0.527
2
UniProt:Q96G30 MRAP2
0.527
2
UniProt:P55899 FCGRN
0.527
2
UniProt:Q5TF58 IFFO2
0.527
2
UniProt:Q06124 PTPN11
4
p-Y542,Y580-PTPN11 [cytosol]
(R-HSA-162573)
PTPN11 [cytosol]
(R-HSA-162563)
PTPN11 [nucleoplasm]
(R-HSA-8937745)
p-Y542-PTPN11 [cytosol]
(R-HSA-1369081)
0.519
2
UniProt:Q9ULH0 KIDINS220
2
p-Y1095-KIDINS220 [cytosol]
(R-HSA-169869)
KIDINS220 [cytosol]
(R-HSA-169880)
0.483
2
UniProt:Q9UBH6 S53A1
0.483
2
UniProt:Q86VI4 LAP4B
0.463
2
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